ZFIN ID: ZDB-GENE-030131-9512
Gene Name: coronin, actin binding protein, 1A
Gene Symbol: coro1a    Nomenclature History

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Previous Names: fj83g12, wu:fj83g12 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Involved in brain development; central nervous system projection neuron axonogenesis; and eye development. Is expressed in several structures, including ball; hematopoietic cell; hematopoietic system; pronephros; and thymus. Human ortholog(s) of this gene implicated in coronin-1A deficiency. Orthologous to human CORO1A (coronin 1A).
Genome Resources: Alliance (1),  Gene:100002113 (1),  Ensembl(GRCz11):ENSDARG00000054610 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015166Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-coro1a N/A 2
    MO2-coro1a N/A 3
    MO3-coro1a N/A 1
    DISEASE ASSOCIATED WITH coro1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    coronin-1A deficiency Alliance Immunodeficiency 8 615401
    DISEASE ASSOCIATED WITH coro1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Molecular Function actin filament binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA coro1a-201 (1)    Ensembl 1813
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM coro1a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    tg(coro1a:dsred) coro1a DsRed Danio rerio 1 1
    Tg(coro1a:DsRedx) coro1a DsRedx Danio rerio 1 4
    Tg(coro1a:EGFP) coro1a EGFP Danio rerio 2 39
    Tg(coro1a:Hsa.PAK1-Hsa.KRAS) coro1a Danio rerioHomo sapiens 1 1
    Tg(coro1a:Kaede) coro1a Kaede Danio rerio 1 1
    Tg(coro1a:LIFEACT-DsRed) coro1a DsRedLIFEACT Danio rerio 1 1
    Tg(coro1a:LOXP-DsRedx-LOXP-GFP) coro1a DsRedxGFPLOXP Danio rerio 1 3
    tg(coro1a:mcoln1a) coro1a mcoln1a Danio rerio 1 1
    Tg(coro1a:mertka) coro1a mertka Danio rerio 1 1
    tg(coro1a:nlrc3l-egfp) coro1a EGFPnlrc3l Danio rerio 1 1
    Tg(coro1a:RaichuEV) coro1a RaichuEV Danio rerio 1 1
    Tg2(coro1a:Kaede) coro1a Kaede Danio rerio 1 1
    MARKER RELATIONSHIPS
    coro1a Contained in: [BAC] DKEYP-71F10 (1)
    coro1a Encodes: [EST] fj83g12
    [cDNA] MGC:63766 (1), MGC:175070 (1), MGC:198116 (1), MGC:198120 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201114 (1) 1766 nt
    Genomic GenBank:CR936397 (1) 173317 nt
    Select Tool
    Polypeptide UniProtKB:Q7SX58 (1) 455 aa
    Sequence Information (all 25)
    ORTHOLOGY for coro1a ( Chr: 3 )
    CITATIONS (49)