Gene

ppiaa

ID
ZDB-GENE-030131-8556
Name
peptidylprolyl isomerase Aa (cyclophilin A)
Symbol
ppiaa Nomenclature History
Previous Names
  • ppia
  • fa93g09
  • wu:fa93g09
  • wu:fb05e11
  • wu:fb13h02
  • wu:fb15a05
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have cyclosporin A binding activity; peptidyl-prolyl cis-trans isomerase activity; and unfolded protein binding activity. Predicted to be involved in protein refolding and response to hypoxia. Is expressed in adipose tissue; cerebellum; digestive system; eye; and midbrain. Orthologous to human PPIA (peptidylprolyl isomerase A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppiaa Human Ortholog
No data available
Associated With ppiaa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
Domain IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Family IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
Homologous_superfamily IPR029000 Cyclophilin-like domain superfamily
Domain Details Per Protein
Protein Length Cyclophilin-like domain superfamily Cyclophilin-type peptidyl-prolyl cis-trans isomerase Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
UniProtKB:B8JKN6 164
UniProtKB:Q499A7 164
UniProtKB:A0A2R8QTQ3 132
UniProtKB:B8JKN7 104
UniProtKB:Q6TNR5 164
UniProtKB:Q6PC65 183
UniProtKB:Q7ZWJ9 190
UniProtKB:Q6P5J4 184
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations