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ZIRC
ZFIN ID: ZDB-GENE-030131-8103
Gene Name: optineurin
Gene Symbol: optn
Sequence Ontology ID : SO:0001217

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Attributions

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Previous Names: si:ch211-240l19.3, wu:fj52f04, zgc:66386, zgc:77868

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have K63-linked polyubiquitin modification-dependent protein binding activity. Involved in axonogenesis and vesicle localization. Predicted to localize to the Golgi apparatus and  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ibl51 Small Deletion Unknown Unknown CRISPR
la015529Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa143 Point Mutation Unknown Premature Stop
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH optn HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    amyotrophic lateral sclerosis type 12 Amyotrophic lateral sclerosis 12 613435
    primary open angle glaucoma Glaucoma 1, open angle, E 137760
    {Glaucoma, normal tension, susceptibility to} 606657
    DISEASE ASSOCIATED WITH optn VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component Golgi apparatus (more)
    Molecular Function K63-linked polyubiquitin modification-dependent protein binding (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA optn-201 (1) 2455
    optn-202 (1) 1614
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM optn No data available
    MARKER RELATIONSHIPS
    optn Contained in: [BAC] CH211-220P15 (1) (order this), CH211-240L19 (1) (order this)
    optn Encodes: [EST] fj52f04
    [cDNA] MGC:66386 (1) (order this), MGC:77868 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001100066 (1) 2455 bp
    Genomic GenBank:CR407595 (1) 206289 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A5WUQ0 (1) 517 aa
    Sequence Clusters UniGene:79390 (1)
    Sequence Information (all 25)
    ORTHOLOGY for optn ( Chr: 4 )
    CITATIONS (35)