Gene

ctps1a

ID
ZDB-GENE-030131-808
Name
CTP synthase 1a
Symbol
ctps1a Nomenclature History
Previous Names
  • ctps
  • ctpsa
  • cb1040 (1)
  • wu:fb49e03 (1)
  • wu:fe17b03 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable CTP synthase activity and identical protein binding activity. Acts upstream of or within notochord development. Predicted to be active in cytoophidium and cytoplasm. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; nervous system; and pectoral fin bud. Human ortholog(s) of this gene implicated in immunodeficiency 24. Orthologous to human CTPS1 (CTP synthase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Dzaki et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ctps1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 24 Alliance Immunodeficiency 24 615897
Associated With ctps1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017456 CTP synthase, N-terminal
Domain IPR017926 Glutamine amidotransferase
Domain IPR033828 CTP synthase GATase domain
Family IPR004468 CTP synthase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR029062 Class I glutamine amidotransferase-like
Domain Details Per Protein
Protein Length Class I glutamine amidotransferase-like CTP synthase CTP synthase GATase domain CTP synthase, N-terminal Glutamine amidotransferase P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A3QJW5 595
UniProtKB:Q6PEI7 591
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations