ZFIN ID: ZDB-GENE-030131-6223
Gene Name: suppressor of fused homolog (Drosophila)
Gene Symbol: sufu
Sequence Ontology ID : SO:0000704

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Previous Names: Su(fu) (1), dre, dreumes, fi39e05, sb:eu762, wu:fi39e05

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu762]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
tm146d Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-sufu (1), MO2-sufu (1), MO3-sufu (1), MO4-sufu (1), MO5-sufu (1)
    PHENOTYPE
    Data: 17 figures from 12 publications
    Observed in: anal fin, anatomical system, ceratohyal cartilage, chondrocyte differentiation (all 27) expand
    DISEASE ASSOCIATED WITH sufu HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    medulloblastoma Medulloblastoma, desmoplastic 155255
    nevoid basal cell carcinoma syndrome Basal cell nevus syndrome 109400
    {Meningioma, familial, susceptibility to} 607174
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of smoothened signaling pathway (more)
    Cellular Component Hedgehog signaling complex (more)
    Molecular Function protein binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007768 (1)
  • InterPro:IPR016591 (1)
  • InterPro:IPR020941 (1)
  • InterPro:IPR024314 (1)
  • Pfam:PF05076 (1)
  • Pfam:PF12470 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000052058 (1) 2748
    ottdart00000052059 (1) 2748
    aberrant processed transcript ottdart00000052061 (1) 724
    ncRNA sufu-004 (1) 976
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    Ab1-sufu (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sufu No data available
    MARKER RELATIONSHIPS
    sufuContained in: [BAC] CH211-195E19 (1) (order this), CH211-264D7 (1) (order this), DKEY-261G4 (1) (order this)
    sufuContains: [SNP] rs3728538 (1)
    sufuEncodes: [EST] eu762 (1), fi39e05, tdsubc_2a6
    [STS] chunp30108
    [cDNA] MGC:55464 (1) (order this), MGC:175081 (1) (order this), MGC:193047 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201309 (1) 2764bp
    Genomic GenBank:CR559945 (1) 186151bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IN62 (1) 485aa
    Sequence Clusters UniGene:162079 (1)
    Sequence Information (all 31)
    OTHER sufu GENE PAGES
  • Alliance (1)
  • Gene:100001615 (1)
  • VEGA:OTTDARG00000036539 (1)
  • Ensembl(GRCz10):ENSDARG00000056801 (1)
  • ORTHOLOGY for sufu (Chr: 13)
    CITATIONS (42)