ZFIN ID: ZDB-GENE-030131-5306
Gene Name: cleavage and polyadenylation factor I subunit 1
Gene Symbol: clp1
Sequence Ontology ID : SO:0000704

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Previous Names: fa28a12, wu:fa28a12 (1)

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity; involved in brain development and spinal cord motor neuron differentiation; predicted to localize to the mRNA cleavage factor  ...
GENE EXPRESSION
All Expression Data: Fig. S3 from Schaffer et al., 2014
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
amc1 Point Mutation Unknown Premature Stop ENU
amc2 Point Mutation Unknown Missense ENU
sa6358 Point Mutation Unknown Splice Site ENU
PHENOTYPE
Data: 3 figures from Schaffer et al., 2014
Observed in:
DISEASE ASSOCIATED WITH clp1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
pontocerebellar hypoplasia type 10 Pontocerebellar hypoplasia, type 10 615803
DISEASE ASSOCIATED WITH clp1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process brain development (more)
Cellular Component mRNA cleavage factor complex (more)
Molecular Function ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity (more)
GO Terms (all 22)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR010655 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR028606 (1)
  • InterPro:IPR032319 (1)
  • InterPro:IPR032324 (1)
  • InterPro:IPR038238 (1)
  • InterPro:IPR038239 (1)
  • Pfam:PF06807 (1)
  • Pfam:PF16573 (1)
  • Pfam:PF16575 (1)
  • EC:2.7.1.78 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA clp1-001 (1) 4292
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM clp1 No data available
    MARKER RELATIONSHIPS
    clp1Contained in: [BAC] DKEYP-121D2 (1)
    clp1Encodes: [EST] fa28a12
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001346238 (1)
    Genomic GenBank:CR855307 (1) 167962bp
    Select Tool
    Polypeptide UniProtKB:E7F3I6 (1)
    Sequence Clusters UniGene:149160 (1)
    Sequence Information (all 10)
    OTHER clp1 GENE PAGES
  • Alliance (1)
  • Gene:565621 (1)
  • VEGA:OTTDARG00000041130 (1)
  • Ensembl(GRCz11):ENSDARG00000063663 (2)
  • ORTHOLOGY for clp1 (Chr: 14)
    CITATIONS (21)