Gene

rnf2

ID
ZDB-GENE-030131-5243
Name
ring finger protein 2
Symbol
rnf2 Nomenclature History
Previous Names
  • fa19h05
  • ring1b
  • wu:fa19h05
  • wz4566 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have chromatin binding activity and ubiquitin protein ligase activity. Involved in several processes, including animal organ morphogenesis; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and pectoral fin development. Predicted to localize to MLL1 complex; PRC1 complex; and nuclear body. Is expressed in brain; eye; gonad; muscle; and pectoral fin. Orthologous to human RNF2 (ring finger protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
16 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rnf2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Luo-Schoch-Yamamoto syndrome 619460
Associated With rnf2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR001841 Zinc finger, RING-type
Domain IPR032443 RAWUL domain
Family IPR037937 E3 ubiquitin-protein ligase RING2
Family IPR043540 E3 ubiquitin-protein ligase RING1/RING2
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length E3 ubiquitin-protein ligase RING1/RING2 E3 ubiquitin-protein ligase RING2 RAWUL domain Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site
UniProtKB:X1WCS5 85
UniProtKB:A0A0H2UKC6 338
UniProtKB:Q803I4 336
UniProtKB:B2GNY0 336
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations