Gene

e2f6

ID
ZDB-GENE-030131-513
Name
E2F transcription factor 6
Symbol
e2f6 Nomenclature History
Previous Names
  • fb34f06
  • si:ch211-195d17.2
  • THAP-E2F6 fusion gene (1)
  • wu:fb34f06
  • zgc:136607
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With e2f6 Human Ortholog
No data available
Associated With e2f6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003316 E2F/DP family, winged-helix DNA-binding domain
Domain IPR006612 THAP-type zinc finger
Domain IPR032198 E2F transcription factor, CC-MB domain
Family IPR015633 E2F Family
Family IPR015635 Transcription factor E2F6
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Homologous_superfamily IPR037241 E2F-DP heterodimerization region
Homologous_superfamily IPR038441 THAP-type zinc finger superfamily
Domain Details Per Protein
Protein Length E2F/DP family, winged-helix DNA-binding domain E2F-DP heterodimerization region E2F Family E2F transcription factor, CC-MB domain THAP-type zinc finger THAP-type zinc finger superfamily Transcription factor E2F6 Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q29RF1 313
UniProtKB:F1Q565 405
UniProtKB:Q5TZC4 406
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations