ZFIN ID: ZDB-GENE-030131-395
Gene Name: apoptosis inhibitor 5
Gene Symbol: api5    Nomenclature History

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Previous Names: api5l1 (1), sr:nyz021, wu:fb26c03

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to localize to nucleus. Is expressed in heart. Orthologous to human API5 (apoptosis inhibitor 5).
Genome Resources: Alliance (1),  Gene:321676 (1),  Ensembl(GRCz11):ENSDARG00000033597 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7144608]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30752 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH api5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH api5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of apoptotic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function lipid binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA api5-201 (1)    Ensembl 2649
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM api5 No data available
    MARKER RELATIONSHIPS
    api5 Contained in: [BAC] CH211-147K10 (1)
    api5 Encodes: [EST] fb26c03, IMAGE:7144608 (1), nyz021 (1)
    [cDNA] MGC:66211 (1), MGC:174147 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199540 (1) 1624 nt
    Genomic GenBank:CR376745 (1) 186587 nt
    Select Tool
    Polypeptide UniProtKB:R4GDP5 (1) 529 aa
    Sequence Information (all 24)
    ORTHOLOGY for api5 ( Chr: 25 )
    CITATIONS (26)