ZFIN ID: ZDB-GENE-030131-3207
Gene Name: TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Gene Symbol: taf2    Nomenclature History

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Previous Names: fc30f02, fc56a05, wu:fc30f02, wu:fc56a05

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have chromatin binding activity and transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and transcription initiation from RNA polymerase II promoter. Predicted to localize to transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TAF2 (TATA-box binding protein associated factor 2).
Genome Resources: Alliance (1),  Gene:324486 (1),  Ensembl(GRCz11):ENSDARG00000102307 (1)
GENE EXPRESSION
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2491Tg Transgenic Insertion Intron 2 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22760 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25004 Point Mutation Unknown Premature Stop ENU
    sa28589 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH taf2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal recessive non-syndromic intellectual disability Alliance Mental retardation, autosomal recessive 40 615599
    DISEASE ASSOCIATED WITH taf2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription by RNA polymerase II (more)
    Cellular Component nucleus (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA taf2-201 (1)    Ensembl 4401
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM taf2 No data available
    MARKER RELATIONSHIPS
    taf2 Contained in: [BAC] CH211-93I7 (1), DKEY-59G8 (1) (order this)
    taf2 Contains: [SNP] rs3728264 (1), rs3728265 (1), rs3728266 (1), rs3728267 (1), rs3728268 (1), rs3728269 (1), rs3728270 (1), rs3728271 (1)
    taf2 Encodes: [EST] fc30f02, fc56a05
    [cDNA] MGC:123088 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003835 (1) 4376 nt
    Genomic GenBank:CU104700 (1) 155195 nt
    Select Tool
    Polypeptide UniProtKB:Q32PW3 (1) 1191 aa
    Sequence Information (all 24)
    ORTHOLOGY for taf2 ( Chr: 16 )
    CITATIONS (27)