ZFIN ID: ZDB-GENE-030131-3143
Gene Name: apolipoprotein A-IV b, tandem duplicate 2
Gene Symbol: apoa4b.2    Nomenclature History

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Previous Names: fc28d04, wu:fc10a03, wu:fc28d04 (1), zgc:194131

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have lipid binding activity. Predicted to be involved in lipid transport and lipoprotein metabolic process. Predicted to localize to extracellular region. Is expressed in ball; extension; intestine; yolk; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Alzheimer's disease; colitis; myocardial infarction; and ulcerative colitis. Orthologous to human APOA4 (apolipoprotein A4).
Genome Resources: Alliance (1),  Gene:570354 (1), 
GENE EXPRESSION
All Expression Data: 16 figures from 3 publications
Directly Submitted Expression Data: 12 figures (17 images) from Rauch et al., 2003 [fc28d04]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22836 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22837 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH apoa4b.2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH apoa4b.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lipid transport (more)
    Cellular Component extracellular region (more)
    Molecular Function lipid binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA apoa4b.2-201 (1)    Ensembl 970
    apoa4b.2-202 (1)    Ensembl 811
    apoa4b.2-203 (1)    Ensembl 1046
    apoa4b.2-204 (1)    Ensembl 588
    ncRNA apoa4b.2-002 (1)    Ensembl 617
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM apoa4b.2 No data available
    MARKER RELATIONSHIPS
    apoa4b.2 Contained in: [BAC] DKEY-7F3 (1) (order this)
    apoa4b.2 Encodes: [EST] fc10a03, fc28d04 (order this)
    [cDNA] MGC:194131 (1), MGC:194132 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001128758 (1) 947 nt
    Genomic GenBank:BX004983 (1) 234489 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B3DHC5 (1) 255 aa
    Sequence Information (all 22)
    ORTHOLOGY for apoa4b.2 ( Chr: 16 )
    CITATIONS (30)