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ZIRC
ZFIN ID: ZDB-GENE-030131-2931
Gene Name: nicotinamide phosphoribosyltransferase 2
Gene Symbol: nampt2    Nomenclature History

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Previous Names: namptb (1), im:7051384, wu:fc21g12, wu:fc27h03, wu:fd15d03, zgc:55764

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have cytokine activity; nicotinamide phosphoribosyltransferase activity; and nicotinate-nucleotide diphosphorylase (carboxylating) activity. Predicted to be involved in NAD biosynthetic process and circadian regulation of gene expression. Predicted to localize to the cytoplasm; extracellular space; and nucleus. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase).
Genome Resources: Alliance (1),  Gene:324211 (1),  Ensembl(GRCz11):ENSDARG00000027183 (2)
Note: This gene name was updated because the phylogenetic tree indicates this was the result of a duplication event PRIOR to the divergence of ray- and lobe-fin fishes and not the teleost WGD
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55764]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb83 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb93 Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • la017736Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nampt2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nampt2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process circadian regulation of gene expression (more)
    Cellular Component cytoplasm (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA namptb-201 (1)    Ensembl 2020
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nampt2 No data available
    MARKER RELATIONSHIPS
    nampt2 Contained in: [BAC] CH211-39D24 (1) (order this), DKEY-30J16 (1) (order this)
    nampt2 Encodes: [EST] fc21g12, fc27h03 (1), fd15d03 (1), IMAGE:7051384
    [cDNA] MGC:55764 (1) (order this), MGC:191990 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212668 (1) 2024 bp
    Genomic GenBank:BX324130 (1) 209188 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1RDZ8 (1) 498 aa
    Sequence Clusters UniGene:116955 (1)
    Sequence Information (all 24)
    ORTHOLOGY for nampt2 ( Chr: 11 )
    CITATIONS (29)