Gene

puf60a

ID

ZDB-GENE-030131-2891

Name

poly-U binding splicing factor a

Symbol

puf60a Nomenclature History

Previous Names

fc21a05
wu:fc21a05 (1)
wu:fi43a08

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Is expressed in central nervous system and pharynx. Orthologous to human PUF60 (poly(U) binding splicing factor 60).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from Rauch et al., 2003

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With puf60a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Verheij syndrome	615583

Associated With puf60a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR003954	RNA recognition motif domain, eukaryote
Domain	IPR034209	PUF60, RNA recognition motif 1
Domain	IPR034211	PUF60, RNA recognition motif 2
Domain	IPR034212	PUF60, RNA recognition motif 3
Family	IPR006532	Poly-U binding splicing factor, PUF60-like
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Nucleotide-binding alpha-beta plait domain superfamily	Poly-U binding splicing factor, PUF60-like	PUF60, RNA recognition motif 1	PUF60, RNA recognition motif 2	PUF60, RNA recognition motif 3	RNA-binding domain superfamily	RNA recognition motif domain	RNA recognition motif domain, eukaryote
UniProtKB:A0A8M2BAZ4 InterPro	550
UniProtKB:F1QZ57 InterPro	552
UniProtKB:A0A8M2BAV4 InterPro	288
UniProtKB:A0A8M9QNK1 InterPro	352
UniProtKB:A0A2R8QFM1 InterPro	538
UniProtKB:A0A8M9Q9Z9 InterPro	371
UniProtKB:A0A8M2BAQ4 InterPro	533
UniProtKB:A8E4R7 InterPro	518

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	puf60a-202 (1) Ensembl	Havana	930 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	puf60a-204 (1) Ensembl	Havana	795 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	puf60a-205 (1) Ensembl	Havana	1095 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	puf60a-206 (1) Ensembl	Havana	866 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	puf60a-208 (1) Ensembl	Havana	769 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	puf60a-209 (1) Ensembl	Havana	842 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	puf60a-210 (1) Ensembl	Havana	2188 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	puf60a-212 (1) Ensembl	Havana	901 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	puf60a-007 (1) Ensembl	Havana	807 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	puf60a-008 (1) Ensembl	Havana	879 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	puf60a-009 (1) Ensembl	Havana	630 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations