ZFIN ID: ZDB-GENE-030131-2220
Gene Name: farnesyltransferase, CAAX box, beta
Gene Symbol: fntb    Nomenclature History

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Previous Names: wu:fb99h09, zgc:86774

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to contribute to protein farnesyltransferase activity. Involved in cardiac ventricle development. Predicted to localize to protein farnesyltransferase complex. Is expressed in heart. Orthologous to several human genes including CHURC1-FNTB (CHURC1-FNTB readthrough).
Genome Resources: Alliance (1),  Gene:323500 (1),  Ensembl(GRCz11):ENSDARG00000027916 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6900012]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-fntb N/A 1
MO2-fntb N/A 1
DISEASE ASSOCIATED WITH fntb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH fntb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cardiac ventricle development (more)
Cellular Component protein farnesyltransferase complex (more)
Molecular Function catalytic activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA fntb-201 (1)    Ensembl 1665
fntb-203 (1)    Ensembl 574
ncRNA fntb-002 (1)    Ensembl 692
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fntb No data available
MARKER RELATIONSHIPS
fntb Contained in: [BAC] DKEY-11E23 (1) (order this), DKEY-263P20 (1) (order this)
fntb Encodes: [EST] fb99h09, IMAGE:6900012 (1)
[cDNA] MGC:86774 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001002128 (1) 1693 nt
Genomic GenBank:AL928866 (1) 249759 nt Blast at MegaBLAST
Polypeptide UniProtKB:A0A2R8QF89 (1) 449 aa
Sequence Information (all 17)
ORTHOLOGY for fntb ( Chr: 20 )
CITATIONS (25)