ZFIN ID: ZDB-GENE-030131-215
Gene Name: cofilin 1
Gene Symbol: cfl1
Sequence Ontology ID : SO:0000704

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Previous Names: cfl2l, wu:fb17d06, wu:fb18d11, wu:fd59f08, wu:fj34b08

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 13 figures from 6 publications
Directly Submitted Expression Data: 7 figures (13 images) from Rauch et al., 2003 [fb17d06]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  anatomical structure, blastomere, brain, central nervous system (all 21) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi3736aTg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-cfl1 (1), MO2-cfl1 (1), MO3-cfl1 (1)
    PHENOTYPE
    Data: 10 figures from 4 publications
    Observed in: actin polymerization or depolymerization, blastoderm filamentous actin, cell migration involved in gastrulation, cell projection organization (all 29) expand
    DISEASE ASSOCIATED WITH cfl1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cilium assembly (more)
    Cellular Component actin cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002108 (1)
  • InterPro:IPR017904 (1)
  • InterPro:IPR029006 (1)
  • PROSITE:PS51263 (1)
  • Pfam:PF00241 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cfl1-001 (1) 1713
    ncRNA cfl1-002 (1) 471
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-cfl (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cfl1 No data available
    MARKER RELATIONSHIPS
    cfl1Contained in: [BAC] CH211-126C2 (1) (order this)
    cfl1Encodes: [EST] fb17d06 (order this), fb18d11, fd59f08 (1), fj34b08 (1)
    cfl1Has Artifact: [cDNA] MGC:103610 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213641 (1) 1709bp
    Genomic GenBank:CT573152 (1) 134793bp
    Select Tool
    Polypeptide UniProtKB:Q6TH32 (1) 165aa
    Sequence Clusters UniGene:33445 (1)
    Sequence Information (all 17)
    OTHER cfl1 GENE PAGES
  • Gene:321496 (1)
  • VEGA:OTTDARG00000020983 (1)
  • Ensembl(GRCz10):ENSDARG00000021124 (1)
  • ORTHOLOGY for cfl1 (Chr: 14)
    CITATIONS (32)