Gene

chac1

ID
ZDB-GENE-030131-1957
Name
ChaC, cation transport regulator homolog 1 (E. coli)
Symbol
chac1 Nomenclature History
Previous Names
  • cb1014 (1)
  • mgc4504
  • wu:fb93a10 (1)
  • wu:fp64e03
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have Notch binding activity and gamma-glutamylcyclotransferase activity. Involved in glutathione catabolic process. Predicted to localize to trans-Golgi network. Is expressed in several structures, including alar plate midbrain region; nervous system; optic vesicle; periderm; and solid lens vesicle. Orthologous to human CHAC1 (ChaC glutathione specific gamma-glutamylcyclotransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Yadav et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chac1 Human Ortholog
No data available
Associated With chac1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013024 Gamma-glutamyl cyclotransferase-like
Family IPR006840 Glutathione-specific gamma-glutamylcyclotransferase
Homologous_superfamily IPR036568 Gamma-glutamyl cyclotransferase-like superfamily
Domain Details Per Protein
Protein Length Gamma-glutamyl cyclotransferase-like Gamma-glutamyl cyclotransferase-like superfamily Glutathione-specific gamma-glutamylcyclotransferase
UniProtKB:Q5SPB6 196
UniProtKB:A8KBI8 196
UniProtKB:A8KBI9 196
UniProtKB:A4QNY6 196
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-chac1 polyclonal Rabbit
  • WB
Sigma-Aldrich
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations