ZFIN ID: ZDB-GENE-030131-1921
Gene Name: myristoylated alanine-rich protein kinase C substrate b
Gene Symbol: marcksb    Nomenclature History

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Previous Names: macs (1), marcks, wu:fb55c06, wu:fb92d04, wu:fc19b04, wu:fc44a10, zgc:110235

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have calmodulin binding activity and kinase activity. Involved in animal organ development; gastrulation; and respiratory system development. Is expressed in several structures, including nervous system; neural plate; neural rod; neural tube; and neuroectoderm. Orthologous to human MARCKS (myristoylated alanine rich protein kinase C substrate).
Genome Resources: Alliance (1),  Gene:323201 (1),  Ensembl(GRCz11):ENSDARG00000008803 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6903275]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb199 Small Deletion Unknown Unknown CRISPR
ihb200 Indel Unknown Unknown CRISPR
sa6465 Point Mutation Unknown Premature Stop ENU
sa36365 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39154 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-marcksb 2
    MO1-marcksb N/A 2
    MO2-marcksb N/A 1
    MO3-marcksb N/A 1
    DISEASE ASSOCIATED WITH marcksb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH marcksb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Cellular Component cellular_component (more)
    Molecular Function calmodulin binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA marcksb-201 (1)    Ensembl 1919
    ncRNA marcksb-002 (1) 317
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM marcksb No data available
    MARKER RELATIONSHIPS
    marcksb Contained in: [BAC] CH211-266G18 (1)
    marcksb Contains: [SNP] rs3728848 (1)
    marcksb Encodes: [EST] fb55c06, fb92d04, fc19b04, fc44a10 (1), IMAGE:2601723, IMAGE:6903275 (1)
    [cDNA] MGC:110235 (1), MGC:192319 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001015060 (1) 1873 nt
    Genomic GenBank:CU306817 (1) 176617 nt
    Select Tool
    Polypeptide UniProtKB:G4XPM3 (1) 249 aa
    Sequence Information (all 33)
    ORTHOLOGY for marcksb ( Chr: 17 )
    CITATIONS (31)