Gene

alpk2

ID
ZDB-GENE-030131-1868
Name
alpha-kinase 2
Symbol
alpk2 Nomenclature History
Previous Names
  • fb83b04
  • si:ch211-233a1.1
  • wu:fb83b04
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have ATP binding activity and protein serine/threonine kinase activity. Involved in epicardium morphogenesis; heart contraction; and heart development. Predicted to localize to basolateral plasma membrane. Is expressed in adaxial cell; primitive heart tube; and somite. Orthologous to human ALPK2 (alpha kinase 2).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 1 from Hofsteen et al., 2018
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Hofsteen et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alpk2 Human Ortholog
No data available
Associated With alpk2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004166 MHCK/EF2 kinase
Domain IPR007110 Immunoglobulin-like domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold MHCK/EF2 kinase Protein kinase-like domain superfamily
UniProtKB:A0A5F5J769 1037
UniProtKB:F1QU13 1966
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations