ZFIN ID: ZDB-GENE-030131-1437
Gene Name: aftiphilin a
Gene Symbol: aftpha    Nomenclature History

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Previous Names: fb71f09, si:ch73-131e21.7, wu:fb71f09 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have clathrin binding activity. Predicted to be involved in intracellular transport. Predicted to localize to AP-1 adaptor complex and trans-Golgi network membrane. Orthologous to human AFTPH (aftiphilin).
Genome Resources: Alliance (1),  Gene:556043 (1),  Ensembl(GRCz11):ENSDARG00000069249 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028192Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7414 Point Mutation Unknown Missense ENU
    zko1115a Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-aftpha 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aftpha HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH aftpha VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular transport (more)
    Cellular Component AP-1 adaptor complex (more)
    Molecular Function clathrin binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aftpha-201 (1)    Ensembl 2840
    aftpha-202 (1)    Ensembl 713
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aftpha No data available
    MARKER RELATIONSHIPS
    aftpha Contained in: [BAC] CH73-131E21 (1)
    aftpha Encodes: [EST] fb71f09, wz126
    aftpha Has Artifact: [EST] fa06d01
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001145561 (1) 2840 nt
    Genomic GenBank:CU467849 (1) 109423 nt
    Select Tool
    Polypeptide UniProtKB:B8JLD1 (1) 793 aa
    Sequence Information (all 25)
    ORTHOLOGY for aftpha ( Chr: 1 )
    CITATIONS (21)