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ZIRC
ZFIN ID: ZDB-GENE-030131-1263
Gene Name: apolipoprotein A-IV b, tandem duplicate 1
Gene Symbol: apoa4b.1    Nomenclature History

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Previous Names: Apo A-IV (1), apoa4, wu:fb64f03, wu:fb66f09, zgc:122983

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have several functions, including cholesterol binding activity; cholesterol transfer activity; and phosphatidylcholine-sterol O-acyltransferase activator activity. Predicted to be involved in several processes, including lipid homeostasis; lipid transport; and plasma lipoprotein particle organization. Predicted to localize to the chylomicron and high-density lipoprotein particle. Human ortholog(s) of this gene implicated in Alzheimer's disease; colitis; myocardial infarction; and ulcerative colitis. Is expressed in female organism; gut; liver; and yolk syncytial layer. Orthologous to human APOA4 (apolipoprotein A4).
Genome Resources: Alliance (1),  Gene:322543 (1),  Ensembl(GRCz11):ENSDARG00000040298 (2)
GENE EXPRESSION
All Expression Data: 22 figures from 7 publications
Directly Submitted Expression Data: 7 figures (6 images) from Thisse et al., 2004 [IMAGE:6908289]
  7 figures (6 images) from Thisse et al., 2004 [IMAGE:6910484]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH apoa4b.1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH apoa4b.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process lipid transport (more)
Cellular Component extracellular region (more)
Molecular Function lipid binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000074 (1)
  • Pfam:PF01442 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA apoa4b.1-201 (1)    Ensembl 1202
    ncRNA apoa4b.1-002 (1)    Ensembl 417
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM apoa4b.1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:apoa4b.1-mCherry) hsp70l apoa4b.1mCherry Danio rerio 1 2
    MARKER RELATIONSHIPS
    apoa4b.1 Contained in: [BAC] DKEY-7F3 (1) (order this)
    apoa4b.1 Encodes: [EST] fb64f03, fb66f09, IMAGE:6908289 (1) (order this), IMAGE:6910484 (1) (order this), IMAGE:7046195
    [cDNA] MGC:109742 (1) (order this), MGC:122983 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001079861 (1) 1210 bp
    Genomic GenBank:BX004983 (1) 234489 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q567B9 (1) 268 aa
    Sequence Clusters UniGene:77089 (1)
    Sequence Information (all 24)
    ORTHOLOGY for apoa4b.1 ( Chr: 16 )
    CITATIONS (48)