ZFIN ID: ZDB-GENE-030131-1145
Gene Name: microtubule-associated protein 1 light chain 3 beta
Gene Symbol: map1lc3b    Nomenclature History

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Previous Names: Lc3 (1), wu:fb60g11, zgc:56434

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have microtubule binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in autophagy of mitochondrion; cellular response to nitrogen starvation; and macroautophagy. Localizes to cytosol. Is expressed in several structures, including cardiovascular system; central nervous system; liver; neural tube; and pleuroperitoneal region. Orthologous to several human genes including MAP1LC3B (microtubule associated protein 1 light chain 3 beta).
Genome Resources: Alliance (1),  Gene:322425 (1),  Ensembl(GRCz11):ENSDARG00000101127 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH map1lc3b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH map1lc3b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process autophagy (more)
Cellular Component cytosol (more)
Molecular Function microtubule binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA map1lc3b-201 (1)    Ensembl 1816
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-map1lc3 polyclonal Rabbit WB Novus Biologicals, LLC
10
Ab3-map1lc3b polyclonal IgG Rabbit IHC, WB Abcam plc
7
Ab1-map1lc3b polyclonal Rabbit WB MBL International
6
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM map1lc3b
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(CMV:EGFP-map1lc3b) EGFPmap1lc3b Danio rerio 1 28
Tg(CMV:mCherry-map1lc3b) CMV map1lc3bmCherry Danio rerio 1 4
tg(elavl3:egfp-map1lc3b) elavl3 EGFPmap1lc3b Danio rerio 1 1
Tg(fabp10a:EGFP-map1lc3b) fabp10a EGFPmap1lc3b Danio rerio 1 3
Tg(gnat2:GFP-map1lc3b) gnat2 GFPmap1lc3b Danio rerio 1 6
Tg(gnat2:mCherry-GFP-map1lc3b) gnat2 GFPmap1lc3bmCherry Danio rerio 1 1
MARKER RELATIONSHIPS
map1lc3b Contained in: [BAC] CH211-280A23 (1)
map1lc3b Encodes: [EST] fb60g11
[cDNA] MGC:56434 (1), MGC:174548 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_199604 (1) 1805 nt
Genomic GenBank:CU571064 (1) 159278 nt
Select Tool
Polypeptide UniProtKB:Q7ZUD8 (1) 122 aa
Sequence Information (all 16)
ORTHOLOGY for map1lc3b ( Chr: 25 )
CITATIONS (76)