ZFIN ID: ZDB-GENE-030131-1089
Gene Name: annexin A2b
Gene Symbol: anxa2b    Nomenclature History

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Previous Names: wu:fb59b10, zgc:92492 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in intestinal cholesterol absorption. Predicted to localize to cytoplasm. Is expressed in gut and intestine. Human ortholog(s) of this gene implicated in osteonecrosis. Orthologous to several human genes including ANXA2 (annexin A2).
Genome Resources: Alliance (1),  Gene:799806 (1),  Ensembl(GRCz11):ENSDARG00000053625 (1)
GENE EXPRESSION
All Expression Data: 7 figures from 7 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92492]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH anxa2b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH anxa2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intestinal cholesterol absorption (more)
Cellular Component basement membrane (more)
Molecular Function calcium-dependent phospholipid binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA anxa2b-201 (1)    Ensembl 1324
anxa2b-202 (1)    Ensembl 1297
ncRNA anxa2b-003 (1)    Ensembl 313
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM anxa2b
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
TgBAC(anxa2b:RFP) anxa2b RFP Danio rerio 1 3
MARKER RELATIONSHIPS
anxa2b Contained in: [BAC] DKEY-182O15 (1) (order this)
anxa2b Encodes: [EST] fb59b10
[cDNA] MGC:92492 (1), MGC:123147 (1), MGC:174369 (1), MGC:193789 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001105600 (1) 1279 nt
Genomic GenBank:BX927082 (1) 157140 nt
Select Tool
Polypeptide UniProtKB:A8E5G1 (1) 338 aa
Sequence Information (all 27)
ORTHOLOGY for anxa2b ( Chr: 7 )
CITATIONS (29)