ZFIN ID: ZDB-GENE-030131-1016
Gene Name: asparaginyl-tRNA synthetase 1
Gene Symbol: nars1    Nomenclature History

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Previous Names: nars, fb57a10, si:dkey-274m14.2, wu:fb57a10 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; asparagine-tRNA ligase activity; and nucleic acid binding activity. Predicted to be involved in asparaginyl-tRNA aminoacylation. Orthologous to human NARS1 (asparaginyl-tRNA synthetase 1).
Genome Resources: Alliance (1),  Gene:568332 (1),  Ensembl(GRCz11):ENSDARG00000061100 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32322 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37195 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nars1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nars1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process asparaginyl-tRNA aminoacylation (more)
    Molecular Function aminoacyl-tRNA ligase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb
    Domain IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N)
    Domain IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
    Family IPR004522 Asparagine-tRNA ligase
    Domain IPR006195 Aminoacyl-tRNA synthetase, class II
    Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nars-201 (1)    Ensembl 2449
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nars1 No data available
    MARKER RELATIONSHIPS
    nars1 Contained in: [BAC] DKEY-274M14 (1) (order this)
    nars1 Encodes: [EST] fb57a10
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_691656 (1)
    Genomic GenBank:BX511310 (1) 169760 bp
    Select Tool
    Polypeptide UniProtKB:B8A5D3 (1) 556 aa
    Sequence Information (all 20)
    ORTHOLOGY for nars1 ( Chr: 21 )
    CITATIONS (20)