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ZIRC
ZFIN ID: ZDB-GENE-020419-24
Gene Name: minichromosome maintenance complex component 2
Gene Symbol: mcm2
Sequence Ontology ID : SO:0000704

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Previous Names: cb737 (1), chunp6905, MCM2 minichromosome maintenance deficient 2

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits chromatin binding activity; involved in retina development in camera-type eye and thymus development; predicted to localize to the MCM complex and nucleus; orthologous to human MCM2  ...
GENE EXPRESSION
All Expression Data: 11 figures from 5 publications
Directly Submitted Expression Data: 6 figures (14 images) from Thisse et al., 2001 [cb737]
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Day 4 (96.0h-120.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi1244Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi3205Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38175 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38176 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH mcm2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant nonsyndromic deafness 70 ?Deafness, autosomal dominant 70 616968
    DISEASE ASSOCIATED WITH mcm2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cilium assembly (more)
    Cellular Component MCM complex (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 22)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mcm2 No data available
    MARKER RELATIONSHIPS
    mcm2Encodes: [EST] cb737 (1) (order this)
    [cDNA] MGC:55282 (1) (order this), MGC:77255 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173257 (1)
    Polypeptide UniProtKB:A0A0R4IF65 (1) 889aa
    Sequence Clusters UniGene:2291 (1)
    Sequence Information (all 19)
    OTHER mcm2 GENE PAGES
  • Alliance (1)
  • Gene:192338 (1)
  • Ensembl(GRCz11):ENSDARG00000102798 (1)
  • ORTHOLOGY for mcm2 (Chr: 22)
    CITATIONS (38)