ZFIN ID: ZDB-FISH-210115-12
Fish name: TU + MO3-chd7 + MO8-chd7
Genotype: TU
Targeting Reagent: MO3-chd7, MO8-chd7
HUMAN DISEASE MODELED by TU + MO3-chd7 + MO8-chd7
Human Disease Conditions Citations
CHARGE syndrome standard conditions Asad et al., 2019
GENE EXPRESSION
Gene expression in TU + MO3-chd7 + MO8-chd7
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in TU + MO3-chd7 + MO8-chd7
Phenotype Conditions Figures
cranium motor neuron isl2a expression spatial pattern, abnormal standard conditions Fig. 1 from Asad et al., 2019
cranium motor neuron isl2a expression spatial pattern, ameliorated chemical treatment by environment: CHIC-35 Fig. 4 from Asad et al., 2019
cranium motor neuron isl2a expression spatial pattern, ameliorated chemical treatment by environment: procainamide Fig. 4 from Asad et al., 2019
cranium sensory neuron isl2a expression spatial pattern, abnormal standard conditions Fig. 1 from Asad et al., 2019
cranium sensory neuron isl2a expression spatial pattern, ameliorated chemical treatment by environment: procainamide Fig. 4 from Asad et al., 2019
cranium sensory neuron isl2a expression spatial pattern, ameliorated chemical treatment by environment: CHIC-35 Fig. 4 from Asad et al., 2019
eye decreased size, abnormal standard conditions Fig. 1 from Asad et al., 2019
glial cell mbpa expression decreased amount, abnormal standard conditions Fig. 1 from Asad et al., 2019
lateral line glial cell mbpa expression amount, ameliorated chemical treatment by environment: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Fig. 5 from Asad et al., 2019
lateral line glial cell mbpa expression amount, ameliorated chemical treatment by environment: CHIC-35 Fig. 5 from Asad et al., 2019
lateral line glial cell mbpa expression amount, ameliorated chemical treatment by environment: procainamide Fig. 5 from Asad et al., 2019
lateral line glial cell mbpa expression amount, ameliorated chemical treatment by environment: DAPT Fig. 5 from Asad et al., 2019
lateral line glial cell mbpa expression decreased amount, abnormal standard conditions Fig. 5 from Asad et al., 2019
mandibular arch skeleton decreased size, abnormal standard conditions Fig. 1 from Asad et al., 2019
pericardium edematous, abnormal standard conditions Fig. 1 from Asad et al., 2019
perichondrium sox9b expression decreased amount, abnormal chemical treatment by environment: procainamide Fig. 3 from Asad et al., 2019
perichondrium sox9b expression decreased amount, abnormal chemical treatment by environment: CHIC-35 Fig. 3 from Asad et al., 2019
perichondrium sox9b expression decreased amount, abnormal chemical treatment by environment: DAPT Fig. 3 from Asad et al., 2019
perichondrium sox9b expression decreased amount, abnormal standard conditions Fig. 1 from Asad et al., 2019
perichondrium sox9b expression decreased amount, abnormal chemical treatment by environment: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Fig. 3 from Asad et al., 2019
pharyngeal arch cartilage sox9a expression amount, ameliorated chemical treatment by environment: DAPT Fig. 3 from Asad et al., 2019
pharyngeal arch cartilage sox9a expression amount, ameliorated chemical treatment by environment: CHIC-35 Fig. 3 from Asad et al., 2019
pharyngeal arch cartilage sox9a expression amount, ameliorated chemical treatment by environment: procainamide Fig. 3 from Asad et al., 2019
pharyngeal arch cartilage sox9a expression amount, ameliorated chemical treatment by environment: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Fig. 3 from Asad et al., 2019
pharyngeal arch cartilage sox9a expression decreased amount, abnormal standard conditions Fig. 1 from Asad et al., 2019
trunk foxd3 expression amount, ameliorated chemical treatment by environment: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Fig. 5 from Asad et al., 2019
trunk foxd3 expression amount, ameliorated chemical treatment by environment: CHIC-35 Fig. 5 from Asad et al., 2019
trunk foxd3 expression amount, ameliorated chemical treatment by environment: DAPT Fig. 5 from Asad et al., 2019
trunk foxd3 expression increased amount, abnormal standard conditions Fig. 5 from Asad et al., 2019
trunk foxd3 expression increased amount, abnormal chemical treatment by environment: procainamide Fig. 5 from Asad et al., 2019

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