ZFIN Fish: ush2a^rmc1/rmc1

ZFIN ID: ZDB-FISH-181221-10

ZFIN ID: ZDB-FISH-181221-10

HUMAN DISEASE MODELED by ush2a^rmc1/rmc1

Human Disease	Conditions	Citations
Usher syndrome type 2A	standard conditions	Dona et al., 2018

GENE EXPRESSION
Gene expression in ush2a^rmc1/rmc1

RNA expression

Expressed Gene	Structure	Conditions	Figures
ush2a	(not) photoreceptor cell periciliary membrane compartment	standard conditions	Fig. 4 from Dona et al., 2018

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-adgrv1		photoreceptor cell periciliary membrane compartment	standard conditions	Fig. S5 from Dona et al., 2018
Ab1-whrnb		photoreceptor cell periciliary membrane compartment	standard conditions	Fig. 5 from Dona et al., 2018
Ab1-whrna		photoreceptor cell periciliary membrane compartment	standard conditions	Fig. 5 from Dona et al., 2018
Ab1-cetn		photoreceptor cell photoreceptor connecting cilium	standard conditions	Fig. 4, Fig. 5 from Dona et al., 2018 Fig. 6 from Slijkerman et al., 2018
Ab2-ush2a	ush2a	(not) photoreceptor cell periciliary membrane compartment	standard conditions	Fig. 4 from Dona et al., 2018
Ab1-ush2a		(not) photoreceptor cell periciliary membrane compartment	standard conditions	Fig. 4 from Dona et al., 2018 Fig. 6 from Slijkerman et al., 2018

Reporter gene expression No data available

PHENOTYPE
Phenotype in ush2a^rmc1/rmc1

Phenotype	Conditions	Figures
photoreceptor cell ab1-ush2a labeling absent, abnormal	control	Fig. 6 from Slijkerman et al., 2018
photoreceptor cell periciliary membrane compartment ush2a expression absent, abnormal	standard conditions	Fig. 4 from Dona et al., 2018
photoreceptor cell periciliary membrane compartment Ab1-whrna labeling decreased amount, abnormal	standard conditions	Fig. 5 from Dona et al., 2018
photoreceptor cell periciliary membrane compartment ab1-adgrv1 labeling decreased amount, abnormal	standard conditions	Fig. S5 from Dona et al., 2018
photoreceptor cell periciliary membrane compartment Ab1-whrnb labeling decreased amount, abnormal	standard conditions	Fig. 5 from Dona et al., 2018
retina morphology, normal	standard conditions	Fig. S4 from Dona et al., 2018
retina transmission of nerve impulse process quality, abnormal	control	Fig. 7 from Dona et al., 2018
retinal outer nuclear layer apoptotic process increased occurrence, abnormal	constant light, high light intensity	Fig. 6 from Dona et al., 2018
retinal outer nuclear layer apoptotic process increased occurrence, abnormal	control	Fig. 6 from Dona et al., 2018

CITATIONS (2)