ZFIN ID: ZDB-FISH-180928-1
Fish name: pitx2mw709/mw709
Genotype: pitx2mw709/mw709
Targeting Reagent: none
HUMAN DISEASE MODELED by pitx2mw709/mw709
Human Disease Conditions Citations
Axenfeld-Rieger syndrome standard conditions Hendee et al., 2018
GENE EXPRESSION
Gene expression in pitx2mw709/mw709
RNA expression
Expressed Gene Structure Conditions Figures
col1a1a standard conditions Fig. 8 from Hendee et al., 2018
col1a2 standard conditions Fig. 8 from Hendee et al., 2018
col5a2b standard conditions Fig. 8 from Hendee et al., 2018
col5a3b standard conditions Fig. 8 from Hendee et al., 2018
dkk2 standard conditions Fig. 8 from Hendee et al., 2018
foxc1a standard conditions Fig. S1 with image from Hendee et al., 2018
tert standard conditions Fig. 8 from Hendee et al., 2018
wnt3 standard conditions Fig. 8 from Hendee et al., 2018
wnt4 standard conditions Fig. 8 from Hendee et al., 2018
wnt6b standard conditions Fig. 8 from Hendee et al., 2018
wnt7aa standard conditions Fig. 8 from Hendee et al., 2018
wnt9b standard conditions Fig. 8 from Hendee et al., 2018
wnt10a standard conditions Fig. 8 from Hendee et al., 2018
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab9-cdh2 standard conditions Fig. 7 with image from Hendee et al., 2018
Ab3-col1a1a standard conditions Fig. 7 with image from Hendee et al., 2018
Ab1-keratan sulfate standard conditions Fig. 7 with image from Hendee et al., 2018
Reporter gene expression No data available
PHENOTYPE
Phenotype in pitx2mw709/mw709
Phenotype Conditions Figures
annular ligament morphology, abnormal standard conditions Fig. 5 with image from Hendee et al., 2018
anterior chamber eye absent, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
anterior chamber eye decreased size, abnormal standard conditions Fig. 3 with imageFig. 5 with image from Hendee et al., 2018
anterior chamber eye morphology, abnormal standard conditions Fig. 4 with imageFig. 5 with image from Hendee et al., 2018
anterior segment eye cartilage tissue mislocalised, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
anterior segment eye integument mislocalised, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
ceratohyal cartilage malformed, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
ceratohyal cartilage position, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
ceratohyal cartilage size, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
cornea abutting lens capsule, abnormal standard conditions Fig. 5 with image from Hendee et al., 2018
cornea morphology, abnormal standard conditions Fig. 4 with image from Hendee et al., 2018
corneal endothelium Ab9-cdh2 labeling absent, abnormal standard conditions Fig. 7 with image from Hendee et al., 2018
corneal endothelium disorganized, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
corneal endothelium increased thickness, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
corneal endothelium morphology, abnormal standard conditions Fig. 4 with imageFig. 6 with image from Hendee et al., 2018
corneal epithelium Ab9-cdh2 labeling decreased amount, abnormal standard conditions Fig. 7 with image from Hendee et al., 2018
corneal epithelium increased thickness, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
corneal epithelium irregular thickness, abnormal standard conditions Fig. 5 with image from Hendee et al., 2018
corneal epithelium Ab1-keratan sulfate labeling mislocalised, abnormal standard conditions Fig. 7 with image from Hendee et al., 2018
corneal epithelium morphology, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
corneal epithelium undulate, abnormal standard conditions Fig. 5 with image from Hendee et al., 2018
corneal epithelium vacuolated, abnormal standard conditions Fig. 4 with image from Hendee et al., 2018
corneal stroma decreased thickness, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
corneal stroma disorganized, abnormal standard conditions Fig. 7 with image from Hendee et al., 2018
corneal stroma increased thickness, abnormal standard conditions Fig. 4 with image from Hendee et al., 2018
corneal stroma irregular thickness, abnormal standard conditions Fig. 5 with image from Hendee et al., 2018
corneal stroma morphology, abnormal standard conditions Fig. 4 with imageFig. 5 with imageFig. 6 with imageFig. 7 with image from Hendee et al., 2018
corneal stroma position, abnormal standard conditions Fig. 4 with image from Hendee et al., 2018
corneal stroma Ab1-keratan sulfate labeling spatial pattern, abnormal standard conditions Fig. 7 with image from Hendee et al., 2018
corneal stroma Ab3-col1a1a labeling spatial pattern, abnormal standard conditions Fig. 7 with image from Hendee et al., 2018
corneal stroma undulate, abnormal standard conditions Fig. 5 with imageFig. 6 with image from Hendee et al., 2018
ethmoid cartilage morphology, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
ethmoid cartilage size, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
eye absent, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
eye wnt10a expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye tert expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye wnt6b expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye col1a2 expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye col1a1a expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye wnt9b expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye col5a2b expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye wnt3 expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye col5a3b expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye wnt7aa expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye wnt4 expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye dkk2 expression decreased amount, abnormal standard conditions Fig. 8 from Hendee et al., 2018
eye decreased size, abnormal standard conditions Fig. 3 with imageFig. 6 with image from Hendee et al., 2018
eye disorganized, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
eye morphology, abnormal standard conditions Fig. 3 with imageFig. 4 with imageFig. 6 with image from Hendee et al., 2018
eye opacity, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
eye cartilage tissue Ab3-col1a1a labeling mislocalised, abnormal standard conditions Fig. 7 with image from Hendee et al., 2018
iris absent, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
iris decreased size, abnormal standard conditions Fig. 6 with image from Hendee et al., 2018
iris hypoplastic, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
iris ventral region morphology, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
iris stroma morphology, abnormal standard conditions Fig. 4 with imageFig. 5 with image from Hendee et al., 2018
lens elongated, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
lens capsule morphology, abnormal standard conditions Fig. 4 with image from Hendee et al., 2018
Meckel's cartilage malformed, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
Meckel's cartilage size, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
optic fissure closure incomplete, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
palatoquadrate cartilage malformed, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
palatoquadrate cartilage size, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018
ventral mandibular arch morphology, abnormal standard conditions Fig. 3 with image from Hendee et al., 2018

CITATIONS  (1)