ZFIN ID: ZDB-FISH-150901-6638
Fish name: mitfaw2/w2; mpv17a9/a9
Genotype: mitfaw2/w2; mpv17a9/a9
Targeting Reagent: none
HUMAN DISEASE MODELED by mitfaw2/w2; mpv17a9/a9
Human Disease Conditions Citations
influenza viral treatment: unidentified influenza virus Gabor et al., 2014
carcinoma cancer xenotransplantation Sahgal et al., 2019
cancer cancer xenotransplantation Jacquemet et al., 2017
cancer xenotransplantation Fazio et al., 2017
cancer xenotransplantation Couturier et al., 2016
cancer xenotransplantation Dib et al., 2019
leukemia cancer xenotransplantation Corkery et al., 2011
bacterial infectious disease bacterial treatment by injection: Mycobacterium marinum M Commandeur et al., 2020
hepatocellular carcinoma cancer xenotransplantation Bartucci et al., 2017
streptococcal meningitis bacterial treatment by injection: Streptococcus pneumoniae Jim et al., 2016
GENE EXPRESSION
Gene expression in mitfaw2/w2; mpv17a9/a9
RNA expression
Expressed Gene Structure Conditions Figures
actn3a standard conditions Fig 6 with image from Vauti et al., 2020
bcl2l1 control Fig. 9 from Opitz et al., 2011
dlx2a standard conditions Fig 4 with image from Vauti et al., 2020
galcb standard conditions Fig. 1 from Belleri et al., 2020
gnrh2 standard conditions Fig. 3 from London et al., 2019
fasting Fig. 3 from London et al., 2019
gnrh3 standard conditions Fig. 3 from London et al., 2019
fasting Fig. 3 from London et al., 2019
hcrt standard conditions Fig. 1 from London et al., 2019
fasting Fig. 1 from London et al., 2019
kiss1 standard conditions Fig. 3 from London et al., 2019
fasting Fig. 3 from London et al., 2019
kiss2 standard conditions Fig. 3 from London et al., 2019
fasting Fig. 3 from London et al., 2019
mc3r standard conditions Fig. 6 from London et al., 2019
fasting Fig. 6 from London et al., 2019
mc4r standard conditions Fig. 6 from London et al., 2019
fasting Fig. 6 from London et al., 2019
nkx2.4b standard conditions Fig. 1Fig. 9 from Opitz et al., 2011
npvf standard conditions Fig. 3 from London et al., 2019
fasting Fig. 3 from London et al., 2019
npy standard conditions Fig. 1 from London et al., 2019
fasting Fig. 1 from London et al., 2019
pax8 control Fig. 9 from Opitz et al., 2011
pomca standard conditions Fig. 6 from London et al., 2019
fasting Fig. 6 from London et al., 2019
pvalb7 standard conditions Fig 5 with image from Vauti et al., 2020
rac1a standard conditions Fig. 5 with image from Razaghi et al., 2017
shha standard conditions Fig 7 with image from Vauti et al., 2020
slc5a5 standard conditions Fig. 4Fig. 5Fig. 6Fig. 8 from Holloway et al., 2020
Fig. 1Fig. 2Fig. 9 from Opitz et al., 2011
chemical treatment: N-phenylthiourea Fig. 2 from Opitz et al., 2011
tac3b standard conditions Fig. 3 from London et al., 2019
fasting Fig. 3 from London et al., 2019
tg standard conditions Fig. 1Fig. 9 from Opitz et al., 2011
th standard conditions Fig. 6 from London et al., 2019
th2 standard conditions Fig. 6 from London et al., 2019
tshba standard conditions Fig. 2 from Opitz et al., 2011
chemical treatment: N-phenylthiourea Fig. 2 from Opitz et al., 2011
tyr standard conditions Fig. 6 from London et al., 2019
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab2-tnnt2 control Fig. 6 from Pellerin et al., 2020
Reporter gene expression No data available
PHENOTYPE
Phenotype in mitfaw2/w2; mpv17a9/a9
Phenotype Conditions Figures
eye lacks all parts of type iridophore, abnormal standard conditions Fig. 1 with image from Antinucci et al., 2016
eye iridophore absent, abnormal standard conditions Fig. 2 from White et al., 2008
female organism brain th2 expression decreased amount, abnormal standard conditions Fig. 6 from London et al., 2019
female organism brain th expression decreased amount, abnormal standard conditions Fig. 6 from London et al., 2019
female organism brain pomca expression decreased amount, abnormal standard conditions Fig. 6 from London et al., 2019
female organism brain tyr expression decreased amount, abnormal standard conditions Fig. 6 from London et al., 2019
female organism brain mc3r expression decreased amount, abnormal standard conditions Fig. 6 from London et al., 2019
female organism brain pomca expression decreased amount, abnormal fasting Fig. 6 from London et al., 2019
female organism brain mc3r expression increased amount, abnormal fasting Fig. 6 from London et al., 2019
integument translucent, abnormal standard conditions Fig. 1 from White et al., 2008
integument iridophore absent, abnormal standard conditions Fig. 2 from White et al., 2008
integument melanocyte absent, abnormal standard conditions Fig. 2 from White et al., 2008
iridophore absent, abnormal standard conditions Fig. 1 from White et al., 2008
larval melanophore stripe melanocyte absent, abnormal standard conditions Fig. 1 with image from Antinucci et al., 2016
male organism brain npvf expression increased amount, abnormal fasting Fig. 3 from London et al., 2019
male organism brain tac3b expression increased amount, abnormal fasting Fig. 3 from London et al., 2019
melanoblast galcb expression absent, abnormal standard conditions Fig. 1 from Belleri et al., 2020
melanocyte absent, abnormal standard conditions Fig. 1 from White et al., 2008
melanocyte galcb expression absent, abnormal standard conditions Fig. 1 from Belleri et al., 2020
melanophore stripe melanocyte absent, abnormal standard conditions Fig. 1 with image from Antinucci et al., 2016
retinal pigmented epithelium pigmented, normal standard conditions Fig. 1 with image from Antinucci et al., 2016
retinal pigmented epithelium melanocyte present, normal standard conditions Fig. 2 from White et al., 2008
swimming decreased length, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Lange et al., 2013
swimming increased length, abnormal standard conditions Fig. 3 with image from Lange et al., 2013
swimming increased velocity, abnormal standard conditions Fig. 2 with imageFig. 3 with image from Lange et al., 2013
swimming velocity, normal standard conditions Fig. 1 with image from Lange et al., 2013
swimming behavior decreased duration, abnormal standard conditions Fig. 1 with image from Lange et al., 2013
swimming behavior duration, normal standard conditions Fig. 2 with imageFig. 3 with image from Lange et al., 2013
whole organism decreased life span, abnormal bacterial treatment by injection: Streptococcus pneumoniae Fig. 1 with image from Jim et al., 2016
whole organism decreased size, abnormal standard conditions Fig. 2 with imageFig. 3 with image from Lange et al., 2013
whole organism viable, normal standard conditions text only from White et al., 2008
whole organism carcinoma decreased size, abnormal cancer xenotransplantation Fig. 7 from Dib et al., 2019
whole organism T-cell neoplasms present, abnormal cancer xenotransplantation Fig. 1 from Bentley et al., 2015

CITATIONS  (57)