ZFIN Fish: y7Tg

ZFIN ID: ZDB-FISH-150901-5696

Fish name:	y7Tg
Genotype:	y7Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by y7Tg

Human Disease	Conditions	Citations
cancer	cancer xenotransplantation	Kolapalli et al., 2020

GENE EXPRESSION
Gene expression in y7Tg

RNA expression

Expressed Gene	Structure	Conditions	Figures
lama1	fin somite	standard conditions	Fig. 2 from Chaudhury et al., 2020
vash1	endothelial cell	standard conditions	Fig. 1. from Bastos de Oliveira et al., 2021

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab7-GFP		posterior cardinal vein endothelial cell	control	Fig. 4. from Bastos de Oliveira et al., 2021
Ab5-akt		cardinal system endothelial cell dorsal aorta endothelial cell	control	Fig. 3 from Kim et al., 2014
Ab9-mapk		endothelial cell	standard conditions	Fig. 5 from Baek et al., 2019
Ab5-prox1		common cardinal vein nucleus cranial vasculature vascular lymphangioblast facial lymphatic network nucleus posterior cardinal vein angiogenic sprout trunk lymph vasculature	standard conditions	Fig. 2 from Arnold et al., 2022 Fig. 4. from Bastos de Oliveira et al., 2021 Fig. 5 from Vogrin et al., 2019
Ab1-smad		(not) endothelial cell nucleus	standard conditions	Fig. 2 , Fig. 3 , Fig. S3 from Laux et al., 2013
Ab2-fn		atrioventricular canal	control	Fig. 5 from Steed et al., 2016
Ab-MF20		myocardium ventricular myocardium	standard conditions	Fig. 3 from Abrial et al., 2022 Fig. S1 from Schumacher et al., 2013
zn-8		heart endothelial cell	control	Fig. 1 from Steed et al., 2016

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
EGFP	aortic arch blood vessel endothelial cell aortic arch 1 endothelial cell atrial endocardium nucleus atrioventricular canal atrioventricular canal endocardium basal communicating artery endothelial cell blood cell blood vessel endothelial cell nucleus bulbus arteriosus endothelial cell cardiac jelly cardinal system endothelial cell caudal division of the internal carotid artery endothelial cell common cardinal vein vascular endothelium cranial blood vessel cranial vasculature dorsal aorta blood vessel endothelial cell endocardial precursor endocardium endothelial cell nucleus facial lymphatic network nucleus heart internal carotid artery endothelial cell intersegmental vessel lymph vessel endothelium endothelial cell myocardium parachordal vessel posterior cardinal vein nucleus presumptive bulbus arteriosus endothelial cell primordial midbrain channel endothelial cell thoracic duct trunk lymph vasculature trunk vasculature vascular endothelium nucleus ventricular endocardium nucleus	standard conditions	45 figures from 35 publications
	endothelial cell nucleus	chemical treatment: antagonist	Fig. 1 from Chen et al., 2017

PHENOTYPE
Phenotype in y7Tg

Phenotype	Conditions	Figures
intersegmental vessel endothelial cell decreased amount, abnormal	chemical treatment: antagonist	Fig. 1 from Chen et al., 2017
ventral aorta endothelial cell decreased amount, abnormal	chemical treatment by environment: inhibitor	Fig 6 from Watterston et al., 2019

CITATIONS (95)