ZFIN Fish: s939Tg

ZFIN ID: ZDB-FISH-150901-5347

Fish name:	s939Tg
Genotype:	s939Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by s939Tg
No data available

GENE EXPRESSION
Gene expression in s939Tg

RNA expression No data available

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-bhmt		hepatocyte	control	Fig. 4 from Wu et al., 2017
Ab-2F11		cholangiocyte intrahepatic bile duct epithelial cell	control	Fig. 2 from So et al., 2017 Fig. 4 from Wu et al., 2017
Ab-2F11		intrahepatic bile duct epithelial cell	chemical treatment by environment: CHIR 99021	Fig. 2 from So et al., 2017

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
mCherry	cholangiocyte nucleus (not) hepatocyte intrahepatic bile duct epithelial cell nucleus melanocyte pancreatic B cell	standard conditions	FIGURE 7 from Min et al., 2020 Fig. 5 from Ahmed Alfar et al., 2017 Fig. 1, Fig. 2, Fig. 6 from So et al., 2017 Fig. 3 , Fig. 4 from Wu et al., 2017 Fig. 5 from Eom et al., 2015 Fig. 3 from Ningappa et al., 2015
	intrahepatic bile duct epithelial cell pancreatic B cell primary islet	chemical treatment by environment: XAV939	Fig. 5 from Ahmed Alfar et al., 2017 Fig. 1, Fig. 2, Fig. 6 from So et al., 2017

PHENOTYPE
Phenotype in s939Tg

Phenotype	Conditions	Figures
bile canaliculus malformed, abnormal	chemical treatment by environment: XAV939	Fig. 1 from So et al., 2017
bile canaliculus malformed, abnormal	chemical treatment by environment: CHIR 99021	Fig. 2 from So et al., 2017
bile ductule decreased length, abnormal	chemical treatment by environment: CHIR 99021	Fig. 2 from So et al., 2017
bile ductule decreased length, abnormal	chemical treatment by environment: XAV939	Fig. 1, Fig. 6 from So et al., 2017
bile ductule disconnected, abnormal	chemical treatment by environment: CHIR 99021	Fig. 2 from So et al., 2017
bile ductule disconnected, abnormal	chemical treatment by environment: XAV939	Fig. 1 from So et al., 2017
bile ductule increased thickness, abnormal	chemical treatment by environment: XAV939	Fig. 1 from So et al., 2017
bile ductule increased thickness, abnormal	chemical treatment by environment: CHIR 99021	Fig. 2 from So et al., 2017
bile ductule malformed, abnormal	chemical treatment by environment: XAV939	Fig. 1 from So et al., 2017
bile ductule malformed, abnormal	chemical treatment by environment: CHIR 99021	Fig. 2 from So et al., 2017
cholangiocyte aggregated, abnormal	chemical treatment: tyrphostin AG 1478	Fig. 4 from Ningappa et al., 2015
intrahepatic bile duct development disrupted, abnormal	chemical treatment: tyrphostin AG 1478	Fig. 4 from Ningappa et al., 2015
intrahepatic bile duct epithelial cell increased amount, abnormal	chemical treatment by environment: dimethyloxalylglycine	FIGURE 7 from Min et al., 2020
liver and biliary system cell population proliferation process quality, normal	chemical treatment: tyrphostin AG 1478	Fig. S7 from Ningappa et al., 2015
primary islet mCherry expression increased distribution, abnormal	chemical treatment by environment: hydrogen peroxide	Fig. 5 from Ahmed Alfar et al., 2017
primary islet pancreatic B cell mCherry expression increased distribution, abnormal	chemical treatment by environment: hydrogen peroxide	Fig. 5 from Ahmed Alfar et al., 2017

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