ZFIN ID: ZDB-FISH-150901-28559
Fish name: mpv17a9/a9
Genotype: mpv17a9/a9
Targeting Reagent: none
HUMAN DISEASE MODELED by mpv17a9/a9
Human Disease Conditions Citations
mitochondrial DNA depletion syndrome standard conditions Martorano et al., 2019
GENE EXPRESSION
Gene expression in mpv17a9/a9
RNA expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in mpv17a9/a9
Phenotype Conditions Figures
aerobic respiration decreased occurrence, abnormal standard conditions Fig. 3 from Martorano et al., 2019
eye lacks all parts of type iridophore, abnormal standard conditions Fig. 1 with image from Antinucci et al., 2016
larval melanophore stripe melanocyte decreased amount, abnormal standard conditions Fig. 1 with image from Antinucci et al., 2016
liver dihydroorotase activity decreased efficacy, abnormal standard conditions Fig. 6 with image from Martorano et al., 2019
liver mitochondrial crista absent, abnormal standard conditions Fig. 2 with image from Martorano et al., 2019
liver mitochondrion increased size, abnormal standard conditions Fig. 2 with image from Martorano et al., 2019
oxidative phosphorylation decreased occurrence, abnormal standard conditions Fig. 3 from Martorano et al., 2019
post-vent region has fewer parts of type iridophore, abnormal chemical treatment by injection: dihydroorotic acid Fig. 6 with imageFig. S4 with image from Martorano et al., 2019
post-vent region has fewer parts of type iridophore, abnormal chemical treatment by environment: dATP, chemical treatment by environment: dGTP Fig. 5 with image from Martorano et al., 2019
post-vent region has fewer parts of type iridophore, abnormal standard conditions Fig. 5 with imageFig. 6 with imageFig. S4 with image from Martorano et al., 2019
post-vent region has fewer parts of type iridophore, ameliorated chemical treatment by injection: orotic acid Fig. 6 with imageFig. S4 with image from Martorano et al., 2019
post-vent region has fewer parts of type iridophore, ameliorated chemical treatment by environment: dGTP, chemical treatment by environment: dATP, chemical treatment by environment: dUTP Fig. 5 with image from Martorano et al., 2019
post-vent region has fewer parts of type iridophore, ameliorated chemical treatment by environment: dUTP Fig. 5 with image from Martorano et al., 2019
retinal pigmented epithelium pigmented, normal standard conditions Fig. 1 with image from Antinucci et al., 2016
whole organism mpv17l expression increased amount, abnormal standard conditions Fig. 1 with image from Martorano et al., 2019
whole organism mitochondrial chromosome decreased amount, abnormal control Fig. 6 with image from Martorano et al., 2019
whole organism mitochondrial chromosome decreased amount, ameliorated chemical treatment by injection: orotic acid Fig. 6 with image from Martorano et al., 2019
whole organism mitochondrial respirasome decreased amount, abnormal standard conditions Fig. 3 from Martorano et al., 2019

CITATIONS  (8)