ZFIN Fish: nop10^hi2578Tg/hi2578Tg

ZFIN ID: ZDB-FISH-150901-26747

ZFIN ID: ZDB-FISH-150901-26747

Fish name:	nop10^{hi2578Tg/hi2578Tg}
Genotype:	nop10^{hi2578Tg/hi2578Tg}
Targeting Reagent:	none

HUMAN DISEASE MODELED by nop10^{hi2578Tg/hi2578Tg}

Human Disease	Conditions	Citations
dyskeratosis congenita	standard conditions	Pereboom et al., 2011

GENE EXPRESSION
Gene expression in nop10^{hi2578Tg/hi2578Tg}

RNA expression

Expressed Gene	Structure	Conditions	Figures
hbbe1.1	nucleate erythrocyte	standard conditions	Fig. 5 from Pereboom et al., 2011
mybl2a	(not) dorsal aorta hematopoietic stem cell	standard conditions	Fig. 5 from Pereboom et al., 2011
rag1	(not) T cell	standard conditions	Fig. 5 from Pereboom et al., 2011
rpl11	whole organism	chemical treatment: pharmaceutical	Fig. 4 from Pereboom et al., 2011
rps7	whole organism	chemical treatment: pharmaceutical	Fig. 4 from Pereboom et al., 2011
runx1	(not) dorsal aorta hematopoietic stem cell	standard conditions	Fig. 5 from Pereboom et al., 2011
tp53	whole organism	standard conditions	Fig. 3, Fig. 4 from Pereboom et al., 2011
	whole organism	gamma ray	Fig. 3 from Pereboom et al., 2011

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-rpl5		whole organism	chemical treatment: pharmaceutical	Fig. 4 from Pereboom et al., 2011
Ab1-rpl11	rpl11	whole organism	chemical treatment: pharmaceutical	Fig. 4 from Pereboom et al., 2011
Ab6-tp53	tp53	whole organism	control	Fig. 3, Fig. 4 from Pereboom et al., 2011
Ab6-tp53		whole organism	gamma ray	Fig. 3 from Pereboom et al., 2011

Reporter gene expression No data available

PHENOTYPE
Phenotype in nop10^{hi2578Tg/hi2578Tg}

Phenotype	Conditions	Figures
apoptotic process increased occurrence, abnormal	gamma ray	Fig. 3 from Pereboom et al., 2011
dorsal aorta hematopoietic stem cell decreased amount, abnormal	standard conditions	Fig. 5 from Pereboom et al., 2011
eye decreased size, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011 text only from Amsterdam et al., 2004
gut hypoplastic, abnormal	standard conditions	text only from Amsterdam et al., 2004
gut immature, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011
head decreased size, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011 text only from Amsterdam et al., 2004
liver hypoplastic, abnormal	standard conditions	text only from Amsterdam et al., 2004
liver immature, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011
midbrain hindbrain boundary morphology, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011
nucleate erythrocyte decreased amount, abnormal	standard conditions	Fig. 5 from Pereboom et al., 2011
pericardium edematous, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011 text only from Amsterdam et al., 2004
primitive hemopoiesis disrupted, abnormal	standard conditions	Fig. 5 from Pereboom et al., 2011
ribosomal small subunit assembly disrupted, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011
rRNA processing disrupted, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011
swim bladder uninflated, abnormal	standard conditions	Fig. 1 from Pereboom et al., 2011
thigmotaxis decreased process quality, abnormal	standard conditions	text only from Pereboom et al., 2011
whole organism dead, abnormal	standard conditions	text only from Pereboom et al., 2011
whole organism chromosome, telomeric region length, normal	standard conditions	Fig. 2 from Pereboom et al., 2011

CITATIONS (4)