ZFIN Fish: y1Tg + MO1-tnnt2a

ZFIN ID: ZDB-FISH-150901-25452

ZFIN ID: ZDB-FISH-150901-25452

Fish name:	y1Tg + MO1-tnnt2a
Genotype:	y1Tg
Targeting Reagent:	MO1-tnnt2a

HUMAN DISEASE MODELED by y1Tg + MO1-tnnt2a
No data available

GENE EXPRESSION
Gene expression in y1Tg + MO1-tnnt2a

RNA expression

Expressed Gene	Structure	Conditions	Figures
hsd3b	interrenal primordium	standard conditions	Fig. 5 from Liu et al., 2006

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-tjp1		endothelial cell cell junction intersegmental vessel cell junction	standard conditions	Fig. 2 from Sauteur et al., 2014

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
EGFP	basilar artery caudal vein plexus central artery cranial vasculature dorsal aorta endothelial cell intersegmental vessel posterior cardinal vein primordial hindbrain channel primordial midbrain channel pronephric glomerular capillary subintestinal vein trunk vasculature	standard conditions	Fig. 2 from Sauteur et al., 2014 Fig. 3 from Fujita et al., 2011 Fig. 4 from Wang et al., 2011 Fig. 2 from Chou et al., 2010 Fig. 6, Fig. S1, Fig. S3, Fig. S6 from Hogan et al., 2008

PHENOTYPE
Phenotype in y1Tg + MO1-tnnt2a

Phenotype	Conditions	Figures
adrenal gland development lacking processual parts cell migration, abnormal	standard conditions	Fig. 2 from Chou et al., 2010
basilar artery decreased diameter, abnormal	standard conditions	Fig. 3 from Fujita et al., 2011
basilar artery structure, normal	standard conditions	Fig. 3 from Fujita et al., 2011
blood circulation absent, abnormal	standard conditions	Fig. 3 from Fujita et al., 2011
blood circulation disrupted, abnormal	standard conditions	Fig. S1 from Hogan et al., 2008
caudal vein endothelial cell elongated, normal	standard conditions	Fig. 6, Fig. S6 from Hogan et al., 2008
caudal vein plexus decreased size, abnormal	standard conditions	Fig. S6 from Hogan et al., 2008
central artery decreased diameter, abnormal	standard conditions	Fig. 3 from Fujita et al., 2011
central artery structure, normal	standard conditions	Fig. 3 from Fujita et al., 2011
cranial vasculature unlumenized, abnormal	standard conditions	Fig. S3 from Hogan et al., 2008
interrenal primordium position, normal	standard conditions	Fig. 2 from Chou et al., 2010
intersegmental vessel blood vessel lumenization process quality, abnormal	standard conditions	Fig. S1 from Sauteur et al., 2014
primordial midbrain channel shape, normal	standard conditions	Fig. S1 from Hogan et al., 2008
pronephric glomerular capillary increased size, abnormal	standard conditions	Fig. 2 from Chou et al., 2010
pronephric glomerulus right side unfused from pronephric glomerulus left side, abnormal	standard conditions	Fig. 2 from Chou et al., 2010
subintestinal vein constricted, normal	standard conditions	Fig. S3 from Hogan et al., 2008
vascular endothelium increased size, abnormal	standard conditions	Fig. 2 from Chou et al., 2010
vascular endothelium mislocalised, abnormal	standard conditions	Fig. 2 from Chou et al., 2010

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