ZFIN Fish: WT + MO1-igf1ra + MO2-igf1ra

ZFIN ID: ZDB-FISH-150901-1877

ZFIN ID: ZDB-FISH-150901-1877

Fish name:	WT + MO1-igf1ra + MO2-igf1ra
Genotype:	WT
Targeting Reagent:	MO1-igf1ra , MO2-igf1ra

HUMAN DISEASE MODELED by WT + MO1-igf1ra + MO2-igf1ra
No data available

GENE EXPRESSION
Gene expression in WT + MO1-igf1ra + MO2-igf1ra

RNA expression

Expressed Gene	Structure	Conditions	Figures
cldna	otic vesicle	standard conditions	Fig. 4 from Schlueter et al., 2006
cxcl12a	whole organism	standard conditions	Fig. 7 from Schlueter et al., 2007
cxcr4b	whole organism	standard conditions	Fig. 7 from Schlueter et al., 2007
ddx4	primordial germ cell	standard conditions	Fig. 1 from Schlueter et al., 2007
myod1	musculature system	standard conditions	Fig. 5 from Schlueter et al., 2006
myog	somite	standard conditions	text only from Schlueter et al., 2006
nkx2.5	heart tube	standard conditions	Fig. 4 from Schlueter et al., 2006
rx1	optic cup	standard conditions	Fig. 4 from Schlueter et al., 2006

Protein expression

Antibody	Structure	Conditions	Figures
Ab-SV2	CaP motoneuron axon	standard conditions	Fig. 5 from Schlueter et al., 2006
Ab-F59	cardiac ventricle fast muscle cell slow muscle cell	standard conditions	Fig. 4, Fig. 5 from Schlueter et al., 2006
zn-5	retinal ganglion cell	standard conditions	Fig. 4 from Schlueter et al., 2006

Reporter gene expression No data available

PHENOTYPE
Phenotype in WT + MO1-igf1ra + MO2-igf1ra

Phenotype	Conditions	Figures
anterior crista primordium aplastic, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
CaP motoneuron axon decreased functionality, abnormal	standard conditions	Fig. 5 from Schlueter et al., 2006
cardiac ventricle hypoplastic, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
cardiac ventricle structure, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
ear development disrupted, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
embryo development delayed, abnormal	standard conditions	Fig. 3 from Schlueter et al., 2006
eye development disrupted, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
fast muscle cell decreased amount, abnormal	standard conditions	Fig. 5 from Schlueter et al., 2006
heart decreased size, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
heart contraction decreased rate, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
heart morphogenesis delayed, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
inner ear hair cell absent, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
lateral crista primordium aplastic, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
muscle contraction decreased occurrence, abnormal	standard conditions	Fig. 5 from Schlueter et al., 2006
posterior crista primordium aplastic, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
retinal ganglion cell absent, abnormal	standard conditions	Fig. 4 from Schlueter et al., 2006
slow muscle cell decreased amount, abnormal	standard conditions	Fig. 5 from Schlueter et al., 2006
somite decreased amount, abnormal	standard conditions	Fig. 3 from Schlueter et al., 2006
whole organism dead, abnormal	standard conditions	text only from Schlueter et al., 2006
whole organism decreased length, abnormal	standard conditions	Fig. 3 from Schlueter et al., 2006

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