ZFIN ID: ZDB-FIG-191007-13
Nicholas et al., 2019 - Temporal characterization of optic fissure basement membrane composition suggests nidogen may be an initial target of remodeling. Developmental Biology   452(1):43-54 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Prim-5 to Pec-fin

Fig. 3

Collagen IV expression during optic fissure formation and fusion. A) WISH for zebrafish collagen IV (col4) genes a1-a6 at 24hpf. At 24hpf, only collagen IV a1 and a2 had optic fissure expression (yellow arrow heads). Col4 a3-a6 were all detected in the retinal periphery and in the developing lens. B) WISH time course for col4 a1 and a2 expression from 24 to 65hpf. Both col4 a1 and a2 had detectable expression in the optic fissure up to 56hpf (yellow arrow heads).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
col4a1 WT standard conditions Prim-5 head ISH
Prim-5 optic fissure ISH
Prim-15 optic furrow ISH
Long-pec head ISH
Long-pec optic furrow ISH
Pec-fin eye ISH
col4a2 WT standard conditions Prim-5 head ISH
Prim-5 optic fissure ISH
Prim-15 optic furrow ISH
Long-pec head ISH
Long-pec optic furrow ISH
Pec-fin eye ISH
col4a3 WT standard conditions Prim-5 solid lens vesicle ISH
Long-pec lens ISH
col4a4 WT standard conditions Prim-5 solid lens vesicle ISH
Long-pec lens ISH
col4a5 WT standard conditions Prim-5 head ISH
Prim-5 solid lens vesicle ISH
Long-pec eye ISH
Long-pec head ISH
col4a6 WT standard conditions Prim-5 eye ISH
Prim-5 solid lens vesicle ISH
Long-pec eye ISH
Long-pec head ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
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Reprinted from Developmental Biology, 452(1), Nicholas, C., Weaver, M., Piedade, W.P., Vocking, O., Famulski, J.K., Temporal characterization of optic fissure basement membrane composition suggests nidogen may be an initial target of remodeling, 43-54, Copyright (2019) with permission from Elsevier. Full text @ Dev. Biol.