|ZFIN ID: ZDB-FIG-190328-34|
Fig. 4 Phenotype of the CTCF morphants. 1-cell to 2-cell embryos were injected with mo-aug or mo-sp. A range of phenotypes was found at 24 hpf, from wild type, mild and severe phenotypes. Different structures were affected: a. Forebrain, b. Midbrain, c. Hindbrain, d. Eye, e. Notochord f. Somites. The percentages and the median of embryos with a mild or severe phenotype are shown in the graph. The statistical difference is noted with an asterisk (n = 4 assays, p = 0.006 for mo-aug; n = 9 assays, p = 0.2609 for mo-sp; one-tailed unpaired t-tests).
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Reprinted from Mechanisms of Development, 154, Carmona-Aldana, F., Zampedri, C., Suaste-Olmos, F., Murillo-de-Ozores, A., Guerrero, G., Arzate-Mejía, R., Maldonado, E., Navarro, R., Chimal-Monroy, J., Recillas-Targa, F., CTCF knockout reveals an essential role for this protein during the zebrafish development, 51-59, Copyright (2018) with permission from Elsevier. Full text @ Mech. Dev.