FIGURE

Fig. 1

ID
ZDB-FIG-180103-37
Publication
Yan et al., 2017 - RETRACTED: Chemical inhibition reveals differential requirements of signaling pathways in krasV12- and Myc-induced liver tumors in transgenic zebrafish.
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Fig. 1

Effect of inhibition of VEGF/FGF on krasV12- and Myc-induced liver enlargement.

7 dpf fabp10+, kras+ or Myc+ larvae were treated with either 1 μM SU5402 or 1 μM SU6668 in the presence of 10 μg/ml Dox and 2D liver size was measured based on images. (AC) Representative images of 7 dpf fabp10+ control larvae. (DF) Representative images of 7 dpf kras+ larvae. (GI) Representative images of 7 dpf Myc+ larvae. (J) Quantification of liver sizes for kras+ larvae (K) Quantification of liver sizes for Myc+ larvae. N = 20 from each groups; statistical significance: *p < 0.05, Scale bar = 20 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
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