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Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-170522-1
Esser et al., 2017 - The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation. Cardiovascular research   113(2):222-223 Full text @ Cardiovasc. Res.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Terms:
Stage: Prim-5
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Protruding-mouth

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
npas4a y1Tg standard conditions Prim-5 caudal vein plexus ISH
Prim-5 posterior cardinal vein ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
y1Tg + MO1-npas4b + MO2-npas4a standard conditions Prim-5 dorsal longitudinal anastomotic vessel hypoplastic, abnormal
Prim-5 intersegmental vessel decreased length, abnormal
Prim-5 intersegmental vessel malformed, abnormal
Long-pec dorsal longitudinal anastomotic vessel hypoplastic, abnormal
Long-pec intersegmental vessel decreased length, abnormal
Long-pec intersegmental vessel malformed, abnormal
Protruding-mouth dorsal longitudinal anastomotic vessel hypoplastic, abnormal
Protruding-mouth intersegmental vessel decreased length, abnormal
Protruding-mouth intersegmental vessel malformed, abnormal
Protruding-mouth sprouting angiogenesis disrupted, abnormal
Full text @ Cardiovasc. Res.