FIGURE

Fig. 1

ID

ZDB-FIG-170424-2

Publication

Otis et al., 2017 - Intestinal epithelial cell Caveolin 1 regulates fatty acid and lipoprotein cholesterol plasma levels

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Fig. 1

Cav1 and caveolae localize to the basolateral and lateral PM of enterocytes. (A) Live imaging of Tg(hsp70l:cav1-eGFP) (6 dpf) zebrafish larvae shows localization of Cav1-eGFP to the lateral and basolateral plasma membranes (PM) of enterocytes, but not the luminal brush border. One enterocyte is outlined. (B) Mean fluorescence intensity, in relative units, of Cav1-eGFP in subcellular regions of larval enterocytes. Data is mean±s.e.m, n=3: nine fish per replicate, three areas of each region per fish; groups with different letters are significantly different (one-way ANOVA, P<0.05). (C,D) Representative EM images of caveola vesicles observed on the basolateral and lateral PMs of larval (6 dpf) (C) and adult (D) zebrafish enterocytes. BB, brush border; L, lateral membrane; B, basolateral membrane; I, intracellular; c, caveolae. Scale bars: 100 nm.

Expression Data

Gene:	EGFP
Fish:	c668Tg (AB)
Condition:	heat shock
Anatomical Terms:	enterocyte basolateral plasma membrane enterocyte lateral plasma membrane
Stage:	Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.