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General Information
ZIRC
ZFIN ID: ZDB-FIG-161014-13
Flanagan-Steet et al., 2016 - Cathepsin-Mediated Alterations In TGFß-Related Signaling Underlie Disrupted Cartilage and Bone Maturation Associated With Impaired Lysosomal Targeting. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research   31(3):535-48 Full text @ J. Bone Miner. Res.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibody:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Day 4
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Day 4

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP y1Tg standard conditions Day 4 Meckel's cartilage chondrocyte IHC
Day 4 palatoquadrate cartilage chondrocyte IHC
y1Tg + MO1-gnptab standard conditions Day 4 Meckel's cartilage chondrocyte IHC
Day 4 palatoquadrate cartilage chondrocyte IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-ctsk IHC y1Tg standard conditions Day 4 chondrocyte intracellular
IHC Day 4 Meckel's cartilage chondrocyte
IHC Day 4 palatoquadrate cartilage chondrocyte
IHC y1Tg + MO1-gnptab standard conditions Day 4 chondrocyte extracellular space
IHC Day 4 chondrocyte intracellular
IHC Day 4 Meckel's cartilage chondrocyte
IHC Day 4 palatoquadrate cartilage chondrocyte
Phenotype Details
Fish Conditions Stage Phenotype
y1Tg + MO1-gnptab standard conditions Day 4 chondrocyte extracellular space ab1-ctsk labeling mislocalised, abnormal
Full text @ J. Bone Miner. Res.