FIGURE

Fig. 9

ID

ZDB-FIG-160706-15

Publication

Raman et al., 2016 - aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 9

The loss of aPKC function and overexpression of MLCK-CA results in formation of Latrunculin resistant stable microridges. Phalloidin stainings of has/apkc sibling and mutant embryos (a) and wild type and MLCK-CA overexpression embryos (e) treated with Latrunculin A. Visualization of the spread and frequency of ridge lengths and medians from the given genotypes and treatments using bean plots (b,f). Estimation of percentage frequency distribution of ridges in short (0-5 µm), intermediate (5-20 µm), long (20-100 µm) and very long (>100 µm) categories (c,g). Estimation of cell wise means and variances of ridge lengths based on phalloidin stainings (d,h). In b,d,f and h, the distributions sharing the same alphabet do not differ significantly (Dunn’s multiple comparisons test, P-value<0.05). The two distributions in ((h) top), WT DMSO and MLCK-CA+LatA, are different at P=0.061. Error bars in c and g are for the s.d. Scale bars in a and e are equivalent to 10 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT prkci^m567/m567
Condition:	chemical treatment: latrunculin A
Observed In:	peridermal cell actin-based cell projection
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.