FIGURE

Fig. 7

ID
ZDB-FIG-160517-7
Publication
Banote et al., 2016 - β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner
Other Figures
All Figure Page
Back to All Figure Page
Fig. 7

DAPT inhibition of γ-secretase and reduced Notch1a rescues Mauthner cell number in Appb morphants. RMO44 immunostaining of embryos at 48 hpf (A-D), anterior at the top. DAPT-treated embryo has supernumerary M-cell (A). DAPT treatment of appb MO injected embryos balances the number of M-cell (B). Embryo co-injected with control MO and notch1a MO has supernumerary M-cells (C). Co-injection of appb MO and notch1a MO rescues the number of M-cell (D). Bar graph displays the quantification of M-cell phenotype in DAPT treated (E) and notch1a injected embryos (F). n, number of embryos. Scale bar, 50 µm.

Expression Data
Antibody:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage: Long-pec

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 413(1), Banote, R.K., Edling, M., Eliassen, F., Kettunen, P., Zetterberg, H., Abramsson, A., β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner, 26-38, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.