ZFIN ID: ZDB-FIG-160328-86
Wu et al., 2015 - Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology   29(12):4989-5005 Full text @ FASEB J.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Long-pec
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-25 to Long-pec

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
DsRed2 f1Tg; la116Tg standard conditions Long-pec myocardium nucleus IFL
tln1f102k/f102k ; f2Tg ; la116Tg standard conditions Long-pec myocardium nucleus IFL
GFP f1Tg; la116Tg standard conditions Long-pec endocardium IFL
la116Tg standard conditions Prim-25 intersegmental vessel IFL
Long-pec intersegmental vessel IFL
la116Tg ; tln1f102k/f102k standard conditions Prim-25 intersegmental vessel IFL
Long-pec intersegmental vessel IFL
tln1f102k/f102k ; f2Tg ; la116Tg standard conditions Long-pec endocardium IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
la116Tg ; tln1f102k/f102k standard conditions Long-pec dorsal aorta decreased diameter, abnormal
Long-pec intersegmental vessel GFP expression decreased amount, abnormal
Long-pec posterior cardinal vein decreased diameter, abnormal
tln1f102k/f102k standard conditions Prim-25 blood circulation process quality, normal
Prim-25 blood vasculature spatial pattern, normal
Long-pec brain hemorrhagic, abnormal
Long-pec cardiac muscle cell apoptotic process process quality, normal
Long-pec cardiac muscle cell decreased amount, abnormal
Long-pec cardiac muscle cell decreased size, abnormal
Long-pec cardiac muscle cell proliferation decreased process quality, abnormal
Long-pec heart contraction decreased efficiency, abnormal
Long-pec heart contraction decreased frequency, abnormal
Long-pec heart decreased volume, abnormal
tln1f102k/f102k ; f2Tg ; la116Tg standard conditions Long-pec heart contraction decreased frequency, abnormal
Long-pec heart decreased volume, abnormal
Full text @ FASEB J.