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General Information
ZIRC
ZFIN ID: ZDB-FIG-160222-4
Wang et al., 2015 - Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae. FASEB journal : official publication of the Federation of American Societies for Experimental Biology   29(11):4435-48 Full text @ FASEB J.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibody:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-5 to Day 5
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 5

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
agrp WT control Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
WT + MO1-tnksb standard conditions Prim-5 whole organism RTPCR
WT + MO2-tnksb standard conditions Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
gh1 WT control Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
WT + MO1-tnksb standard conditions Prim-5 whole organism RTPCR
WT + MO2-tnksb standard conditions Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
pomca WT control Prim-5 whole organism RTPCR
Day 5 hypothalamus ISH
Day 5 rostral pars anterior adrenocorticotropic hormone secreting cell ISH
Day 5 whole organism RTPCR
WT standard conditions Day 5 hypothalamus ISH
Day 5 rostral pars anterior adrenocorticotropic hormone secreting cell ISH
WT + MO1-tnksb standard conditions Prim-5 whole organism RTPCR
WT + MO2-tnksb standard conditions Prim-5 whole organism RTPCR
Day 5 hypothalamus ISH
Day 5 pars intermedia melanocyte stimulating hormone secreting cell ISH
Day 5 rostral pars anterior adrenocorticotropic hormone secreting cell ISH
Day 5 whole organism RTPCR
pou1f1 WT control Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
WT + MO1-tnksb standard conditions Prim-5 whole organism RTPCR
WT + MO2-tnksb standard conditions Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
prl WT control Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
WT + MO1-tnksb standard conditions Prim-5 whole organism RTPCR
WT + MO2-tnksb standard conditions Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
tshba WT control Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
WT + MO1-tnksb standard conditions Prim-5 whole organism RTPCR
WT + MO2-tnksb standard conditions Prim-5 whole organism RTPCR
Day 5 whole organism RTPCR
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab2-aMSH IHC WT control Day 5 hypothalamus
IHC Day 5 pars intermedia melanocyte stimulating hormone secreting cell
IHC WT standard conditions Day 5 hypothalamus
IHC Day 5 pars intermedia melanocyte stimulating hormone secreting cell
IHC WT + MO2-tnksb control Day 5 hypothalamus
IHC Day 5 pars intermedia melanocyte stimulating hormone secreting cell
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-tnksb standard conditions Prim-5 whole organism pomca expression decreased amount, abnormal
WT + MO2-tnksb control Day 5 pars intermedia melanocyte stimulating hormone secreting cell ab2-amsh labeling decreased amount, abnormal
WT + MO2-tnksb standard conditions Prim-5 whole organism pomca expression decreased amount, abnormal
WT + MO2-tnksb standard conditions Day 5 pars intermedia melanocyte stimulating hormone secreting cell pomca expression decreased amount, abnormal
WT + MO2-tnksb standard conditions Day 5 whole organism pomca expression decreased amount, abnormal
Full text @ FASEB J.