FIGURE

Fig. 4

ID
ZDB-FIG-151125-21
Publication
Okuda et al., 2015 - A zebrafish model of inflammatory lymphangiogenesis
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Fig. 4

The Vegfr pathway is required for zebrafish intestinal inflammatory lymphangiogenesis. (A-C) Lateral images of intestine in 7dpf lyve1:DsRed2 larvae exposed to TNBS+1% DMSO (A), TNBS+2.5nM tivozanib (B) and TNBS+150nM sunitinib (C). Asterisks indicate intestinal lymphatic sprouts (ILSs). (D,E) Quantification of ILS number (D) and total ILS length (E) in TNBS+1% DMSO treated larvae compared with 2.5nM tivozanib, TNBS+2.5nM tivozanib, 150nM sunitinib and TNBS+150nM sunitinib treated larvae (n≥20). Error bars, ±s.d. **P<0.01, ***P<0.001 by one-way ANOVA with Dunnett′s multiple comparison test. L-IL, left intestinal lymphatics; TD, thoracic duct. Scale bar: 100µm.

Expression Data
Gene:
Fish:
Conditions:
Anatomical Terms:
Stage: Days 7-13

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Conditions:
Observed In:
Stage: Days 7-13

Phenotype Detail
Acknowledgments
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