FIGURE

Fig. 7

ID
ZDB-FIG-151002-12
Publication
Liu et al., 2015 - Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia
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Fig. 7

Enhanced vascular lipid accumulation in apoc2 mutants. (A,B) TG and TC levels in homogenates of 14dpf WT and apoc2 mutant (mut) larvae, normalized to total protein content. Larvae were fed a normal diet. Results are mean±s.e.m.; n=3 in each group; *P<0.05; ***P<0.001 (Student′s t-test). (C,D) Vascular lipid deposits in 14dpf WT (n=8) and apoc2 mutant (n=8) larvae fed a normal diet; **P<0.01 (Student′s t-test). (E) Colocalization of vascular lipid deposits with macrophages in 14dpf apoc2 mutant mpeg1:EGFP zebrafish. (F) Quantification of lipid deposits associated and non-associated with macrophages in apoc2 mutant larvae. Results are mean±s.e.m.; n=7. Scale bars: 50µm.

Expression Data
Gene:
Fish:
Anatomical Term:
Stage: Days 14-20

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Days 14-20

Phenotype Detail
Acknowledgments
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