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Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-150622-7
Scheidecker et al., 2015 - Mutations in TUBGCP4 Alter Microtubule Organization via the γ-Tubulin Ring Complex in Autosomal-Recessive Microcephaly with Chorioretinopathy. American journal of human genetics   96(4):666-74 Full text @ Am. J. Hum. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Antibodies:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Protruding-mouth to Day 5
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Long-pec to Day 4

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression DetailsNo data available
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Qualifier Anatomy
Ab1-rho IHC WT control Protruding-mouth retinal rod cell
IHC WT + MO1-tubgcp4 standard conditions Protruding-mouth Not Detected retinal rod cell
zpr-1 IHC WT control Protruding-mouth - Day 5 retinal cone cell
IHC WT + MO1-tubgcp4 standard conditions Protruding-mouth - Day 5 retinal cone cell
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-tubgcp4 standard conditions Long-pec eye decreased diameter, abnormal
Long-pec eye decreased size, abnormal
Long-pec head decreased size, abnormal
Long-pec trunk anatomical axis decreased length, abnormal
Protruding-mouth eye decreased diameter, abnormal
Protruding-mouth retina cell circular, abnormal
Protruding-mouth retinal cone cell decreased amount, abnormal
Protruding-mouth retinal rod cell absent, abnormal
Day 4 retinal cone cell decreased amount, abnormal
Full text @ Am. J. Hum. Genet.