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General Information
ZIRC
ZFIN ID: ZDB-FIG-150602-45
Rodríguez-Fraticelli et al., 2015 - Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs. Nature cell biology   17(3):241-50 Full text @ Nat. Cell Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibodies:
Fish:
Anatomical Terms:
Stage Range: Day 4 to Days 14-20
PHENOTYPE:
Fish:
Observed In:
Stage Range: Day 4 to Days 14-20

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
GFP pd1114Tg standard conditions Day 6 enterocyte endosome IHC
Day 6 mid intestine epithelium apical region IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab2-rab11 IHC WT standard conditions Day 4 mid intestine epithelium enterocyte
IHC Day 4 mid intestine epithelium recycling endosome
IHC pd1114Tg standard conditions Day 6 enterocyte endosome
IHC Day 6 mid intestine epithelium apical region
IHC Day 6 mid intestine epithelium recycling endosome
IHC pllppd1116/pd1116 standard conditions Day 4 mid intestine epithelium enterocyte
IHC Day 4 mid intestine epithelium recycling endosome
Ab7-cdh1 IHC WT standard conditions Days 14-20 mid intestine epithelium epithelial cell
IHC pllppd1116/pd1116 standard conditions Days 14-20 mid intestine epithelium epithelial cell
Phenotype Details
Fish Conditions Stage Phenotype
pllppd1116/pd1116 standard conditions Day 4 enterocyte recycling endosome mislocalised radially, abnormal
Day 6 digestive tract morphogenesis decreased process quality, abnormal
Day 6 intestinal epithelium malformed, abnormal
Day 6 intestinal epithelium endocytosis decreased occurrence, abnormal
Day 6 intestinal epithelium epithelial cell decreased height, abnormal
Days 14-20 digestive tract morphogenesis decreased process quality, abnormal
Days 14-20 intestinal epithelium malformed, abnormal
Days 14-20 intestinal epithelium apical plasma membrane increased area, abnormal
Full text @ Nat. Cell Biol.