ZFIN ID: ZDB-FIG-150312-39
Lush et al., 2014
- ErbB expressing Schwann cells control lateral line progenitor cells via non-cell-autonomous regulation of Wnt/beta-catenin.
3:e01832 Full text @ Elife
Expression of several Wnt/β-catenin inhibitors are increased in nrg1-3z26.
Control sibling and nrg1-3z26 mutants were fixed at 48 hpf and processed for in situ hybridization. Control larvae show sfrp1a expression in interneuromast and mantle cells (A). Expression of sfrp1a is increased in nrg1-3z26 (B). Control larvae show no expression of wif1 (C) or dkk1b (F) in interneuromast or Schwann cells. Both wif1 (D) and dkk1b (E) are induced in interneuromast cells of nrg1-3z26. (G) Control larvae show expression of dkk2 in primary neuromasts (inset) but not in interneuromast or Schwann cells. (H) In Tg(sox10:DNerbb4) dkk2 is expressed in neuromasts (inset), and is upregulated in interneuromast cells.
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Full text @ Elife