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General Information
ZIRC
ZFIN ID: ZDB-FIG-140814-1
Niu et al., 2014 - The Nuclear Pore Complex Function of Sec13 Protein Is Required for Cell Survival during Retinal Development. The Journal of biological chemistry   289:11971-85 Full text @ J. Biol. Chem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibody:
Fish:
Anatomical Terms:
Stage Range: Prim-5 to Day 5
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Day 4

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
sec13 Ab1-sec13 WT standard conditions Prim-5 whole organism WB
Ab1-sec13 Long-pec whole organism WB
Ab1-sec13 Protruding-mouth retina IHC
Ab1-sec13 Protruding-mouth whole organism WB
Ab1-sec13 Day 4 whole organism WB
Ab1-sec13 Day 5 whole organism WB
Ab1-sec13 sec13sq198/sq198 standard conditions Prim-5 whole organism WB
Ab1-sec13 Long-pec whole organism WB
Ab1-sec13 Protruding-mouth Not Detected retina IHC
Ab1-sec13 Protruding-mouth whole organism WB
Ab1-sec13 Day 4 whole organism WB
Ab1-sec13 Day 5 whole organism WB
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-sec31a + MO1-sec31b standard conditions Long-pec eye decreased size, abnormal
Protruding-mouth eye decreased size, abnormal
Day 4 eye decreased size, abnormal
sec13sq198/sq198 standard conditions Protruding-mouth eye decreased size, abnormal
Protruding-mouth retina disorganized, abnormal
Protruding-mouth retina has fewer parts of type retinal ganglion cell, abnormal
Protruding-mouth retina apoptotic process increased process quality, abnormal
Protruding-mouth retina layer formation process quality, abnormal
Protruding-mouth retinal pigmented epithelium distended, abnormal
Day 4 eye decreased size, abnormal
Day 4 retina layer formation process quality, abnormal
Day 4 retinal pigmented epithelium distended, abnormal
Full text @ J. Biol. Chem.